Adenocarcinoma, Clear Cell
Recent clinical, regulatory, research and industry developments relating to this disease.
Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial with recent milestones.
Clinical MilestonesViewHide
- 2026-05-01DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare TumorsPrimary completion
- 2026-05-01ClinicalDART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare TumorsPrimary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes4
- Carcinoma, Ovarian Epithelial1
- Ovarian Neoplasms1
- Tumor Suppressor Proteins1
- Ubiquitin-Protein Ligases1
Leading journals2
- Journal of the National Comprehensive Cancer Network : JNCCN1
- The New England journal of medicine1
Leading researchers8
- Alvarez RD1
- Armstrong DK1
- Bakkum-Gamez JN1
- Barroilhet L1
- Behbakht K1
- Berchuck A1
- Burns JL1
- Chen HX1
Affiliations (unnormalised)6
- 10Massachusetts General Hospital Cancer Center.1
- 11The University of Texas MD Anderson Cancer Center.1
- 12Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance.1
- 13Memorial Sloan Kettering Cancer Center.1
- 14Moffitt Cancer Center.1
- 15Fox Chase Cancer Center.1
Reference
Authoritative identity, definition & identifiers.
An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.