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Disease
Alveolar Bone Loss
Late-stage therapeutic developmentEmerging research
1
Publications
15
Clinical trials
2019
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
The cytokine network involved in the host immune response to periodontitis.
Research2019-11-05International journal of oral science
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 4 clinical trials with recent milestones.
Major developments
Major clinical milestoneImportant
Primary completion2026-07-15
Major clinical milestoneImportant
Primary completion2026-02-14
Clinical MilestonesViewHide
Recently completed
- 2026-07-15Evaluation of Mesenchymal Stem Cell-Derived Exosomes Versus Platelet-Rich Fibrin (PRF) in Post-Extraction Socket Healing: A Randomized Controlled Clinical Trial.Primary completion
- 2026-04-28Adjunctive Use of Injectable PRF in Non-surgical Periodontal Therapy: Clinical and Microbiological Outcomes ( Split - Mouth Randomized Controlled Trial )Primary completion
- 2026-02-14Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic PeriodontitisPrimary completion
- 2025-12-20A Resorbable Versus a Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants Immediately Loaded: a Multicentre Randomised Controlled TrialPrimary completion
Activity timeline4
- 2026-07-15ClinicalEvaluation of Mesenchymal Stem Cell-Derived Exosomes Versus Platelet-Rich Fibrin (PRF) in Post-Extraction Socket Healing: A Randomized Controlled Clinical Trial.Primary completion
- 2026-04-28ClinicalAdjunctive Use of Injectable PRF in Non-surgical Periodontal Therapy: Clinical and Microbiological Outcomes ( Split - Mouth Randomized Controlled Trial )Primary completion
- 2026-02-14ClinicalClinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic PeriodontitisPrimary completion
- 2025-12-20ClinicalA Resorbable Versus a Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants Immediately Loaded: a Multicentre Randomised Controlled TrialPrimary completion
Clinical trials
The current development programme across all trial phases.
Clinical programme
15
6
6
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Recent publications
Major themes1
- Inflammation1
Leading journals1
- International journal of oral science1
Leading researchers3
- Chen Q1
- Pan W1
- Wang Q1
Affiliations (unnormalised)1
- State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.