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Disease

Ascariasis

Late-stage therapeutic developmentEmerging research
MeSHAscariasis
1
Publications
7
Clinical trials
2023
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

A systematic review of neglected tropical diseases (NTDs) in Myanmar.

Research2023-11-01PLoS neglected tropical diseases

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial with recent milestones (1 completed or reporting results).
Clinical Milestones1View
Results posted 1
Activity timeline1

Clinical trials

4 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
7
All trials
0
Active
4
Late-stage
6
Completed
Late-stage studies

Longitudinal Study of Efficacy of Standard Albendazole Treatment Versus Levamisole/Pyrantel Pamoate on Soil Transmitted Helminth Infections

Phase 4 · Completed · Natural History Museum, United Kingdom

Efficacy and Safety of Moxidectin-albendazole Combination for Trichuris Trichiura Infections in School-aged Children: a Double-blind Randomised Controlled Superiority Trial

Phase 3 · Completed · Jennifer Keiser

Efficacy and Safety of Moxidectin and Albendazole Compared to Ivermectin and Albendazole Co-administration in Adolescents Infected With Trichuris Trichiura: a Randomized Controlled Trial

Phase 2/3 · Completed · Jennifer Keiser

Efficacy and Safety of Combination Moxidectin and Albendazole, Ivermectin and Albendazole and Albendazole Alone in Adolescents and Adults Infected With Trichuris Trichiura: a Randomized Controlled Trial

Phase 3 · Completed · Jennifer Keiser
Recently completed

Efficacy and Safety of Moxidectin-albendazole Combination for Trichuris Trichiura Infections in School-aged Children: a Double-blind Randomised Controlled Superiority Trial

Phase 3 · Completed · Jennifer Keiser

Efficacy and Safety of Combination Moxidectin and Albendazole, Ivermectin and Albendazole and Albendazole Alone in Adolescents and Adults Infected With Trichuris Trichiura: a Randomized Controlled Trial

Phase 3 · Completed · Jennifer Keiser

Efficacy and Safety of Moxidectin and Albendazole Compared to Ivermectin and Albendazole Co-administration in Adolescents Infected With Trichuris Trichiura: a Randomized Controlled Trial

Phase 2/3 · Completed · Jennifer Keiser

Impact of Repeated Anthelminthic Treatment on Malaria in School Children: an Individual Randomized, Double-blind, Placebo-controlled Trial in Western Kenya

N/A · Completed · London School of Hygiene and Tropical Medicine

Longitudinal Study of Efficacy of Standard Albendazole Treatment Versus Levamisole/Pyrantel Pamoate on Soil Transmitted Helminth Infections

Phase 4 · Completed · Natural History Museum, United Kingdom

Efficacy and Nutritional Assessment Following Albendazole and Combined Albendazole/Ivermectin Treatment for Intestinal Helminth Infections in Rural Guatemalan Schoolchildren

N/A · Completed · Centers for Disease Control and Prevention

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

A systematic review of neglected tropical diseases (NTDs) in Myanmar.

PLoS neglected tropical diseases · 2023 · 6 cites
Recent publications

A systematic review of neglected tropical diseases (NTDs) in Myanmar.

PLoS neglected tropical diseases · 2023 · 6 cites
Major themes6
  • Ascariasis1
  • Encephalitis, Japanese1
  • Helminths1
  • Melioidosis1
  • Rickettsia Infections1
  • Tropical Medicine1
Leading journals1
  • PLoS neglected tropical diseases1
Leading researchers6
  • Ashley EA1
  • Cooper BS1
  • Phyo AP1
  • Smithuis F1
  • Swe MMM1
  • White NJ1
Affiliations (unnormalised)4
  • Centre for Tropical Medicine and Global Health1
  • Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit1
  • Mahidol University1
  • Myanmar Oxford Clinical Research Unit (MOCRU)1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.

Identifiers
MeSHAscariasis
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.