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Disease
Blood Loss, Surgical
Late-stage therapeutic developmentEmerging research
1
Publications
17
Clinical trials
2020
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 2 clinical trials expected to report results, the earliest in Q1 2027.
Major developments
Upcoming trial readoutHigh impact
Results expected Q1 20272026-04-28
Upcoming trial readoutImportant
Results expected Q2 20282026-05-14
Clinical MilestonesViewHide
Results expected
- 2026-05-14Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury - A Randomized Control TrialResults expected Q2 2028
- 2026-04-28Topical Tranexamic Acid as a Adjunct to Intravenous Tranexamic Acid in Adult Spinal Deformity SurgeryResults expected Q1 2027
Recently completed
- 2026-07-01Phase II, Randomized, Double Blinded, Placebo Controlled Superiority Trial of Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine AtonyPrimary completion
- 2025-12-01Assessment of Nebulized Tranexamic Acid in Functional Endoscopic Sinus Surgery Using Modena Bleeding Score. A Randomized Double Blinded Controlled Trial.Primary completion
Activity timeline4
- 2026-07-01ClinicalPhase II, Randomized, Double Blinded, Placebo Controlled Superiority Trial of Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine AtonyPrimary completion
- 2026-05-14ClinicalPhenylephrine Tumescence for Hemostasis in Surgery for Burn Injury - A Randomized Control TrialResults expected Q2 2028
- 2026-04-28ClinicalTopical Tranexamic Acid as a Adjunct to Intravenous Tranexamic Acid in Adult Spinal Deformity SurgeryResults expected Q1 2027
- 2025-12-01ClinicalAssessment of Nebulized Tranexamic Acid in Functional Endoscopic Sinus Surgery Using Modena Bleeding Score. A Randomized Double Blinded Controlled Trial.Primary completion
Clinical trials
The current development programme across all trial phases.
Clinical programme
17
4
11
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes1
- Enhanced Recovery After Surgery1
Leading journals1
- Acta orthopaedica1
Leading researchers8
- Gill M1
- Ljungqvist O1
- McDonald DA1
- Middleton RG1
- Reed M1
- Sahota O1
- Wainwright TW1
- Yates P1
Affiliations (unnormalised)6
- Glasgow Caledonian University1
- Golden Jubilee National Hospital1
- Northumbria Healthcare NHS Foundational Trust1
- Nottingham University1
- Nottingham University Hospital1
- Örebro University1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Loss of blood during a surgical procedure.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.