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Disease

Bradycardia

Late-stage therapeutic developmentEmerging research
MeSHBradycardia
2
Publications
13
Clinical trials
1
Related conditions
2024
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Moderate
Key developments
  • 4 clinical trials expected to report results, the earliest in Q3 2026.
Upcoming Milestones
Clinical Milestones7View
Results expected 4
Recently completed 3
Activity timeline7

Clinical trials

12 sponsors · 2 new · 1 completed in the last 12 months (net +2)

The current development programme across all trial phases.

Clinical programme
13
All trials
6
Active
8
Late-stage
6
Completed
Late-stage studies

A Randomized Controlled Trial Evaluating the Effect of the Oxytocin Infusion Rate on Fetal Heart Rate Changes and Maternal-Fetal Outcomes During the Initiation of Combined Spinal-Epidural Labor Analgesia

Phase 4 · Recruiting · Unyime Ituk

A Combination of Levobupivacaine and Lidocaine for Paravertebral Block in Breast Cancer Patients Undergoing Quadrantectomy Causes Greater Hemodynamic Oscillations Than Levobupivacaine Alone

Phase 4 · Active, not recruiting · University Hospital Dubrava

Comparison For Ease Of Spinal Positioning & Duration Of Post-Op Analgesia Between Ultrasound Guided Supra-Inguinal Fascia Iliaca Block Vs Ultrasound Guided Infra-Inguinal Fascia Iliaca Block In Patients Undergoing Thigh & Knee Surgeries

Phase 2/3 · Recruiting · Sahiwal medical college sahiwal

The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients: a Randomized Clinical Trial Protocol

Phase 3 · Recruiting · Università Vita-Salute San Raffaele

Comparison of Effect of Atropine or Ephedrine Pretreatment for Preventing Bradycardia Under Sedation With Dexmedetomidine After Spinal Anesthesia in Elderly Patients

Phase 4 · Completed · Ajou University School of Medicine

Prophylactic Use of Iv Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section Under Spinal Anaesthesia. a Randomized Controlled Trial

Phase 4 · Completed · Assiut University
Recruiting

A Randomized Controlled Trial Evaluating the Effect of the Oxytocin Infusion Rate on Fetal Heart Rate Changes and Maternal-Fetal Outcomes During the Initiation of Combined Spinal-Epidural Labor Analgesia

Phase 4 · Recruiting · Unyime Ituk

Comparison For Ease Of Spinal Positioning & Duration Of Post-Op Analgesia Between Ultrasound Guided Supra-Inguinal Fascia Iliaca Block Vs Ultrasound Guided Infra-Inguinal Fascia Iliaca Block In Patients Undergoing Thigh & Knee Surgeries

Phase 2/3 · Recruiting · Sahiwal medical college sahiwal

The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients: a Randomized Clinical Trial Protocol

Phase 3 · Recruiting · Università Vita-Salute San Raffaele

LEadless Advanced Pacing 2 Chronic Early Feasibility Study

N/A · Recruiting · Abbott Medical Devices

BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System

N/A · Recruiting · Biotronik, Inc.
Recently completed

Treating Intraoperative Bradycardia in Non-cardiac Surgery Patients With Atropine at Heart Rates Below 60 Versus 30 Beats Per Minute and Norepinephrine Requirements: the Randomized RAPID Trial

N/A · Completed · University of Hamburg-Eppendorf

Comparison of Effect of Atropine or Ephedrine Pretreatment for Preventing Bradycardia Under Sedation With Dexmedetomidine After Spinal Anesthesia in Elderly Patients

Phase 4 · Completed · Ajou University School of Medicine

Prophylactic Use of Iv Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section Under Spinal Anaesthesia. a Randomized Controlled Trial

Phase 4 · Completed · Assiut University

Determination of Remifentanil's ED50 for Rapid Sequence Intubation Avoiding Bradycardia and Hypotension in Adults

Phase 3 · Completed · Brasilia University Hospital

Prospective Analysis of Low-Dose Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart

Phase 1 · Completed · Columbia University

Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal Anesthesia

Phase 4 · Completed · Sira Bang

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20212024
Major themes5
  • Heart Failure2
  • Atrial Fibrillation1
  • Cardiac Resynchronization Therapy1
  • Heart Arrest1
  • Pacemaker, Artificial1
Leading journals1
  • European heart journal2
Leading researchers8
  • Auricchio A1
  • Ballantyne C1
  • Barbash IM1
  • Barrabés JA1
  • Bick AG1
  • Boriani G1
  • Braunschweig F1
  • Brignole M1
Affiliations (unnormalised)6
  • Baylor College of Medicine1
  • Brigham and Women's Hospital1
  • Broad Institute of Harvard and MIT1
  • Cardiovascular Research Center and Center for Genomic Medicine1
  • Dana-Farber Cancer Institute1
  • Department of Laboratory Medicine1

Related conditions

1 match

Diseases frequently studied alongside this one. Number shows shared papers.

Heart Failure2

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Identifiers
MeSHBradycardia
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.