Brain Death
Recent clinical, regulatory, research and industry developments relating to this disease.
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial with recent milestones.
Clinical MilestonesViewHide
- 2025-12-01ClinicalCalcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY)-Pilot TrialPrimary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes3
- Graft Rejection1
- Kidney Transplantation1
- Transplantation, Heterologous1
Leading journals1
- The New England journal of medicine1
Leading researchers8
- Ali NM1
- Ayares D1
- Boeke JD1
- Boulton G1
- Burdorf L1
- Cawthon S1
- Dandro A1
- Deterville C1
Affiliations (unnormalised)1
- From the New York University (NYU) Langone Transplant Institute (R.A.M.1
Reference
Authoritative identity, definition & identifiers.
A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.