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Disease
Chronobiology Disorders
Late-stage therapeutic developmentEmerging researchRising momentum
3
Publications
2
Clinical trials
2025
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Clinical trial2026-07-27Status changed to Active, not recruiting · ClinicalTrials.gov
Research2025-07-19Molecular psychiatry
Circadian dysfunction and cardio-metabolic disorders in humans.
Research2024-04-29Frontiers in endocrinology
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 1 clinical trial expected to report results, the earliest in Q3 2026.
Major developments
Upcoming trial readoutHigh impact
Results expected Q3 20262026-07-27
Clinical MilestonesViewHide
Results expected
Activity timeline1
- 2026-07-27ClinicalA Multicenter, Double-blind, Randomized Study to Evaluate the Effects of Tasimelteon vs. Placebo in Participants With Delayed Sleep-Wake Phase Disorder (DSWPD)Results expected Q3 2026
Clinical trials
The current development programme across all trial phases.
Clinical programme
2
2
2
0
Late-stage studies
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20032025
Most influential
Major themes5
- Circadian Rhythm2
- Biological Evolution1
- Bipolar Disorder1
- Cardiovascular Diseases1
- Metabolic Diseases1
Leading journals3
- Frontiers in endocrinology1
- Molecular psychiatry1
- Sleep1
Leading researchers8
- Alessi C1
- Ancoli-Israel S1
- Campbell H1
- Campbell IH1
- Chambers M1
- Cole R1
- Dubsky M1
- Frye MA1
Affiliations (unnormalised)6
- Centre for Clinical Brain Sciences1
- Centre for Global Health1
- Charles University1
- Diabetes Centre1
- Institute of Physiology1
- Mayo Clinic1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Disruptions of the rhythmic cycle of bodily functions or activities.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.