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Disease

Cocaine-Related Disorders

Late-stage therapeutic developmentEmerging research
1
Publications
12
Clinical trials
2003
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.

Research2003-04-01The Journal of neuroscience : the official journal of the Society for Neuroscience

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

No activity recorded in this window. Try a wider timeframe.

Clinical trials

6 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
12
All trials
0
Active
7
Late-stage
6
Completed
Late-stage studies

Efficacy of Quetiapine in the Reduction of Cocaine Use and Cravings in Individuals With Cocaine Dependence

Phase 4 · Completed · Seattle Institute for Biomedical and Clinical Research

Methylphenidate Raclopride PET Test

Phase 4 · Completed · National Institute on Drug Abuse (NIDA)

Pharmacotherapy and Intensive Treatment

Phase 4 · Completed · National Institute on Drug Abuse (NIDA)

Effect of Nefazodone on Relapse in Females With Cocaine Abuse

Phase 3 · Completed · National Institute on Drug Abuse (NIDA)
Recently completed

Efficacy of Quetiapine in the Reduction of Cocaine Use and Cravings in Individuals With Cocaine Dependence

Phase 4 · Completed · Seattle Institute for Biomedical and Clinical Research

Methylphenidate Raclopride PET Test

Phase 4 · Completed · National Institute on Drug Abuse (NIDA)

Pharmacotherapy and Intensive Treatment

Phase 4 · Completed · National Institute on Drug Abuse (NIDA)

Effect of Nefazodone on Relapse in Females With Cocaine Abuse

Phase 3 · Completed · National Institute on Drug Abuse (NIDA)

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003 · 705 cites
Recent publications

Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003 · 705 cites
Leading journals1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers3
  • Kalivas PW1
  • Lapish CC1
  • McFarland K1
Affiliations (unnormalised)1
  • Medical University of South Carolina1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Disorders related or resulting from use of cocaine.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.