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Disease

Colonic Diseases

Late-stage therapeutic developmentEmerging research
MeSHColonic Diseases
1
Publications
11
Clinical trials
1999
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q1 2030.
Upcoming Milestones
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

8 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
11
All trials
1
Active
3
Late-stage
6
Completed
Recently completed

Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon Cleansing

Phase 4 · Completed · Parc de Salut Mar

A Prospective, Randomized, Parallel, Multi-center, Phase 3 Trial to Evaluate Safety and Efficacy of PBK-1701TC

Phase 3 · Completed · Pharmbio Korea Co., Ltd.

A Double-Blind, Placebo Controlled, Phase I Study to Assess Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Oral Doses of GIC-1001 in Normal Healthy Volunteers

Phase 1 · Completed · gicare Pharma Inc.

Randomised, Controlled Trial of Intravenous Saline Pre-hydration in Patients Undergoing Outpatient Colonoscopy

Phase 2 · Completed · The Canberra Hospital

Clinical Study to Test the Efficacy of Herbal Medicine in Relieving Symptoms and Change of Quality of Life of Patients With IBS

Phase 2 · Completed · Chinese University of Hong Kong

A Phase I, Double-Blind, Placebo-Controlled, Randomized, Parallel-Group Study to Evaluate the Safety and Efficacy of a Combination Herbal Therapy (CHT), Versus Placebo in Improving the Overall Quality of Life and Symptoms in Patients With Irritable Bowel Syndrome (IBS)

Phase 1 · Completed · Hadassah Medical Organization

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation.

The Journal of experimental medicine · 1999 · 1,087 cites
Recent publications

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation.

The Journal of experimental medicine · 1999 · 1,087 cites
Leading journals1
  • The Journal of experimental medicine1
Leading researchers5
  • Asseman C1
  • Coffman RL1
  • Leach MW1
  • Mauze S1
  • Powrie F1
Affiliations (unnormalised)1
  • John Radcliffe Hospital1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).

Identifiers
MeSHColonic Diseases
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.