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Disease

Cryptosporidiosis

Late-stage therapeutic developmentEmerging research
MeSHCryptosporidiosis
2
Publications
11
Clinical trials
1
Associated genes
2023
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q1 2027.
Upcoming Milestones
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

6 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
11
All trials
1
Active
1
Late-stage
5
Completed
Recently completed

An Open Label Cryptosporidium Controlled Human Infection Model (CHIM) to Assess the Efficacy and Safety of ABO809 in Healthy Participants

Phase 1 · Completed · Novartis Pharmaceuticals

A Phase II/III Placebo-Controlled Study of Nitazoxanide (NTZ) For Persons With AIDS and Cryptosporidiosis

Phase 2 · Completed · National Institute of Allergy and Infectious Diseases (NIAID)

A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3

Phase 2 · Completed · National Institute of Allergy and Infectious Diseases (NIAID)

Single-Blind Efficacy Evaluation of Intravenous Spiramycin in Subjects With AIDS-Related Cryptosporidial Diarrhea

Phase 1 · Completed · Rhone-Poulenc Rorer

A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS Patients

Phase 1 · Completed · Univax Biologics Inc

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20072023
Major themes6
  • Cryptosporidiosis1
  • Cryptosporidium1
  • Disease Outbreaks1
  • Giardiasis1
  • Global Health1
  • Parasites1
Leading journals1
  • Journal of water and health2
Leading researchers6
  • Karanis P2
  • Bourli P1
  • Eslahi AV1
  • Kourenti C1
  • Smith H1
  • Tzoraki O1
Affiliations (unnormalised)4
  • Medical Faculty and University Hospital1
  • Medical Microbiology Research Center1
  • National Research Center for Protozoan Diseases1
  • School of the Environment1

Associated genes

1 match

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

CEMP10.02

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Intestinal infection with organisms of the genus CRYPTOSPORIDIUM. It occurs in both animals and humans. Symptoms include severe DIARRHEA.

Identifiers
MeSHCryptosporidiosis
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.