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Disease

Dwarfism, Pituitary

Late-stage therapeutic developmentEmerging research
2
Publications
3
Clinical trials
1
Related treatments
2023
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Research-associated treatments

Drugs and agents co-studied with this disease across the research literature — associative, not necessarily established treatments. Number shows shared papers.

Clinical trials

2 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
3
All trials
0
Active
1
Late-stage
2
Completed
Recently completed

Nutrients and Hormones: Effects in Boys With Disordered Growth - Pilot Study

Phase 2 · Completed · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20192023
Major themes4
  • Dwarfism, Pituitary1
  • Human Growth Hormone1
  • Hypopituitarism1
  • Longevity1
Leading journals2
  • Endocrine reviews1
  • Frontiers in endocrinology1
Leading researchers7
  • Aguiar-Oliveira MH1
  • Antoniazzi F1
  • Bartke A1
  • Cavarzere P1
  • Guzzo A1
  • Pietrobelli A1
  • Zaffanello M1
Affiliations (unnormalised)4
  • Federal University of Sergipe1
  • School of Medicine1
  • Southern Illinois University School of Medicine1
  • University of Verona1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from the HYPOTHALAMUS or from the mutations in the growth hormone gene (GH1) in the PITUITARY GLAND. It is also known as Type I pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of HUMAN GROWTH HORMONE during development.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.