Epilepsy, Absence
Recent clinical, regulatory, research and industry developments relating to this disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 2 clinical trials expected to report results, the earliest in Q3 2026.
- Q3 2026A Single-center, Double-blind, Placebo-controlled Crossover Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence Seizures
- Q2 2028A Prospective, Case-control Evaluation of Ketogenic Dietary Therapy for New-onset Childhood Absence Epilepsy
Clinical MilestonesViewHide
- 2026-05-29A Single-center, Double-blind, Placebo-controlled Crossover Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence SeizuresResults expected Q3 2026
- 2026-05-07A Prospective, Case-control Evaluation of Ketogenic Dietary Therapy for New-onset Childhood Absence EpilepsyResults expected Q2 2028
- 2026-05-29ClinicalA Single-center, Double-blind, Placebo-controlled Crossover Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence SeizuresResults expected Q3 2026
- 2026-05-07ClinicalA Prospective, Case-control Evaluation of Ketogenic Dietary Therapy for New-onset Childhood Absence EpilepsyResults expected Q2 2028
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes3
- Epilepsies, Myoclonic1
- Epilepsies, Partial1
- Epilepsy, Absence1
Leading journals2
- Epilepsia1
- The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers8
- Auvin S1
- Coenen AM1
- Cross HJ1
- Guerreiro M1
- Gwer S1
- Hirsch E1
- Lopes da Silva FH1
- Meeren HK1
Affiliations (unnormalised)6
- Aga Khan University1
- Albert Einstein College of Medicine and Montefiore Medical Center1
- Austin Health and Royal Children's Hospital1
- Bambino Gesù Children's Hospital1
- Department of Clinical Neurosciences1
- Institute of Neurological Sciences1
Related conditions
Diseases frequently studied alongside this one. Number shows shared papers.
Reference
Authoritative identity, definition & identifiers.
A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.