Foramen Ovale, Patent
Recent clinical, regulatory, research and industry developments relating to this disease.
Migraine and cardiovascular disease: what cardiologists should know.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes7
- Brain Ischemia1
- Cardiologists1
- Cardiovascular Diseases1
- Foramen Ovale, Patent1
- Migraine Disorders1
- Migraine with Aura1
- Stroke1
Leading journals1
- European heart journal1
Leading researchers8
- Appelman Y1
- Couturier EGM1
- Dahdal J1
- de Winter RJ1
- El Bouziani A1
- Kalkman DN1
- MaassenVanDenBrink A1
- Mehran R1
Affiliations (unnormalised)4
- Department of Clinical and Experimental Cardiology1
- Erasmus MC University Medical Center1
- Heart Center1
- Icahn School of Medicine at Mount Sinai1
Reference
Authoritative identity, definition & identifiers.
A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.