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Disease
Gallbladder Neoplasms
Late-stage therapeutic developmentEmerging research
2
Publications
7
Clinical trials
1
Associated genes
2023
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
NCCN Guidelines® Insights: Biliary Tract Cancers, Version 2.2023.
Research2023-07-01Journal of the National Comprehensive Cancer Network : JNCCN
Overview of current targeted therapy in gallbladder cancer.
Research2020-10-07Signal transduction and targeted therapy
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 1 clinical trial expected to report results, the earliest in Q4 2029.
Major developments
Major clinical milestoneImportant
Primary completion2026-07-31
Upcoming trial readoutImportant
Results expected Q4 20292025-12-02
Clinical MilestonesViewHide
Recently completed
Activity timeline2
- 2026-07-31ClinicalPhase II Basket Study to Evaluate the Tissue-agnostic Efficacy of Anti-Programmed Cell Death Protein 1 (Anti-PD1) Monoclonal Antibody in Patients With Advanced Rare TumorsPrimary completion
- 2025-12-02ClinicalDETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial): An Umbrella-Basket Platform Trial to Evaluate the Efficacy of Targeted Therapies in Rare Adult, Paediatric and Teenage/Young Adult (TYA) Cancers With Actionable Genomic Alterations, Including Common Cancers With Rare Actionable Alterations. Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations.Results expected Q4 2029
Clinical trials
The current development programme across all trial phases.
Clinical programme
7
2
3
4
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
Most influential
Major themes6
- Gallbladder Neoplasms2
- Bile Duct Neoplasms1
- Biliary Tract Neoplasms1
- Cholangiocarcinoma1
- Liver Neoplasms1
- Precision Medicine1
Leading journals2
- Journal of the National Comprehensive Cancer Network : JNCCN1
- Signal transduction and targeted therapy1
Leading researchers8
- Abbott DE1
- Abrams T1
- Ahmed A1
- Anaya DA1
- Anders R1
- Are C1
- Bachini M1
- Benson AB1
Affiliations (unnormalised)6
- Abramson Cancer Center at the University of Pennsylvania.1
- Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.1
- City of Hope National Medical Center.1
- Dana-Farber/Brigham and Women's Cancer Center.1
- Department of General Surgery and Laboratory of General Surgery1
- Duke Cancer Institute.1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Tumors or cancer of the gallbladder.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.