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Disease

Glucosephosphate Dehydrogenase Deficiency

Clinical development underwayEmerging research
1
Publications
2
Clinical trials
1
Associated genes
1
Related proteins
2024
Latest publication
Current focus
Glucose-6-phosphate 1-dehydrogenase biologyTherapeutic developmentMetabolic & lifestyle factors
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

The global role of G6PD in infection and immunity.

Research2024-06-13Frontiers in immunology

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

2 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
2
All trials
0
Active
0
Late-stage
2
Completed
Recently completed
N/A · Completed · Walter Reed Army Institute of Research (WRAIR)
Phase 2 · Completed · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

The global role of G6PD in infection and immunity.

Frontiers in immunology · 2024 · 12 cites
Recent publications

The global role of G6PD in infection and immunity.

Frontiers in immunology · 2024 · 12 cites
Major themes2
  • Glucosephosphate Dehydrogenase1
  • Glucosephosphate Dehydrogenase Deficiency1
Leading journals1
  • Frontiers in immunology1
Leading researchers4
  • Francis RO1
  • Karafin MS1
  • Shah SS1
  • Stone EF1
Affiliations (unnormalised)2
  • Columbia University1
  • Department of Pathology and Laboratory Medicine1

Associated genes

1 match

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.