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Disease

Granuloma

Late-stage therapeutic developmentEmerging research
MeSHGranuloma
1
Publications
12
Clinical trials
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Immune mechanisms of granuloma formation in sarcoidosis and tuberculosis.

Research2024-01-02The Journal of clinical investigation

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 clinical trials with recent milestones (1 completed or reporting results).
Clinical Milestones2View
Recently completed 1
Other updates 1
Activity timeline2

Clinical trials

9 sponsors · 1 new · 1 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
12
All trials
1
Active
2
Late-stage
6
Completed
Late-stage studies

Loteprednol Etabonate Versus Prednisolone Acetate for Anterior Chamber Granulomas: A Randomized Study

Phase 4 · Completed · Fayoum University

Treatment of Tracheostomy Granulomas

Phase 4 · Completed · University of Colorado, Denver
Recently completed

Loteprednol Etabonate Versus Prednisolone Acetate for Anterior Chamber Granulomas: A Randomized Study

Phase 4 · Completed · Fayoum University

Outcome Of Treatment With Silver Nitrate Versus Topical Steroid For Umbilical Granuloma In Terms Of Healing After 3 Weeks Of Treatment

Phase 2 · Completed · Children Hospital and Institute of Child Health, Lahore

Open-label Trial of Tofacitinib in Cutaneous Sarcoidosis and Granuloma Annulare

Phase 1 · Completed · Yale University

Treatment of Tracheostomy Granulomas

Phase 4 · Completed · University of Colorado, Denver

Comparison of Double Ligation and Topical Silver Nitrate for Treatment of Umbilical Granuloma in Children: A Randomized Control Trial

Phase 2 · Completed · Shaheed Zulfiqar Ali Bhutto Medical University

Treatment of Aggressive Central Giant Cell Granuloma

Phase 2 · Completed · Shiraz University of Medical Sciences

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Immune mechanisms of granuloma formation in sarcoidosis and tuberculosis.

The Journal of clinical investigation · 2024 · 52 cites
Recent publications

Immune mechanisms of granuloma formation in sarcoidosis and tuberculosis.

The Journal of clinical investigation · 2024 · 52 cites
Major themes3
  • Mycobacterium tuberculosis1
  • Sarcoidosis1
  • Tuberculosis1
Leading journals1
  • The Journal of clinical investigation1
Leading researchers3
  • Ho LP1
  • Moller DR1
  • Weeratunga P1
Affiliations (unnormalised)2
  • John Hopkins University1
  • Weatherall Institute of Molecular Medicine1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Identifiers
MeSHGranuloma
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.