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Disease

Hand, Foot and Mouth Disease

Late-stage therapeutic developmentEmerging research
MeSHHand, Foot and Mouth Disease
2
Publications
7
Clinical trials
2024
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

5 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
7
All trials
1
Active
6
Late-stage
6
Completed
Late-stage studies

To Evaluate the Lot-to-lot Consistency of Immunogenicity, Safety, and Immune Persistence of Three Consecutive Commercial Manufacturing Batches of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell) in Children Aged 6-35 Months in a Randomized, Blinded Study

Phase 4 · Recruiting · Institute of Medical Biology, Chinese Academy of Medical Sciences

Multiple Centers, Randomized, and Control Trail on the Immunogenicity and Safety of the Simultaneously Vaccination of Inactivated Enterovirus 71 Vaccine (EV71) and Seasonal Influenza Vaccine(SIV)

Phase 4 · Completed · Zhejiang Provincial Center for Disease Control and Prevention

Phase Ⅳ Clinical Trial, to Evaluate the Efficacy of the Enterovirus 71 (EV71) Inactivated Vaccine and Its Correlation With EV71 Antibody Level

Phase 4 · Completed · Sinovac Biotech Co., Ltd

A Phase IV Clinical Trial for Efficacy Evaluation for Inactivated Vaccine (Vero Cell) Against EV71: A Multicenter， Case-control Study.

Phase 4 · Completed · Jiangsu Province Centers for Disease Control and Prevention

Three Batches Consistency, Immunity Duration and Safety of Inactivated Enterovirus 71 Vaccine Post-marketing Among Children Aged 6-35 Months in China

Phase 4 · Completed · Jiangsu Province Centers for Disease Control and Prevention

A Randomized, Controlled Clinical Trial to Evaluate the Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With Measles, Mumps, and Rubella Combined Live Attenuated Vaccine/ Encephalitis Live Attenuated Vaccine

Phase 4 · Completed · Sinovac Biotech Co., Ltd
Recently completed

Multiple Centers, Randomized, and Control Trail on the Immunogenicity and Safety of the Simultaneously Vaccination of Inactivated Enterovirus 71 Vaccine (EV71) and Seasonal Influenza Vaccine(SIV)

Phase 4 · Completed · Zhejiang Provincial Center for Disease Control and Prevention

Phase Ⅳ Clinical Trial, to Evaluate the Efficacy of the Enterovirus 71 (EV71) Inactivated Vaccine and Its Correlation With EV71 Antibody Level

Phase 4 · Completed · Sinovac Biotech Co., Ltd

A Phase IV Clinical Trial for Efficacy Evaluation for Inactivated Vaccine (Vero Cell) Against EV71: A Multicenter， Case-control Study.

Phase 4 · Completed · Jiangsu Province Centers for Disease Control and Prevention

Three Batches Consistency, Immunity Duration and Safety of Inactivated Enterovirus 71 Vaccine Post-marketing Among Children Aged 6-35 Months in China

Phase 4 · Completed · Jiangsu Province Centers for Disease Control and Prevention

A Randomized, Controlled Clinical Trial to Evaluate the Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With Measles, Mumps, and Rubella Combined Live Attenuated Vaccine/ Encephalitis Live Attenuated Vaccine

Phase 4 · Completed · Sinovac Biotech Co., Ltd

Sucralfate to Improve Oral Intake in Children With Infectious Oral Ulcers: a Randomized, Double-blind, Placebo-Controlled Trial

Phase 2 · Completed · University of Texas at Austin

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes3
  • Hand, Foot and Mouth Disease2
  • COVID-191
  • Seasons1
Leading journals2
  • Frontiers in public health1
  • Scientific reports1
Leading researchers8
  • Ding Z1
  • Fu T1
  • Hu X1
  • Lin J1
  • Lu Q1
  • Song Q1
  • Tao L1
  • Wang J1
Affiliations (unnormalised)4
  • Fengxian District Centers for Disease Control and Prevention1
  • Hangzhou Medical College1
  • Microbiology Laboratory1
  • Zhejiang Provincial Center for Disease Control and Prevention1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A mild, highly infectious viral disease of children, characterized by vesicular lesions in the mouth and on the hands and feet. It is caused by coxsackieviruses A.

Identifiers
MeSHHand, Foot and Mouth Disease
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.