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Disease
Hearing Loss, Sensorineural
Late-stage therapeutic developmentEmerging research
2
Publications
18
Clinical trials
2021
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Diabetes mellitus and hearing loss: A review.
Research2021-08-09Ageing research reviews
Research2011-09-01The Journal of neuroscience : the official journal of the Society for Neuroscience
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Moderate
Key developments
- 1 clinical trial expected to report results, the earliest in Q2 2028.
Upcoming Milestones
Major developments
Major trial resultsImportant
Results posted2026-02-04
Major trial resultsImportant
Results posted2025-12-31
Clinical MilestonesView all 11Hide
Results posted
- 2026-02-04Benefits of Bimodal Streaming for MED-EL Cochlear Implants: Early User Experience With the AudioKey Application and Starkey Hearing AidsResults posted
- 2025-12-31Evaluating Design Improvements With SONNET 3 in Experienced Cochlear Implant UsersResults posted
- 2025-12-17A Prospective, Single Centre, Single-blinded, Within-subject Investigation, on the Effect of Stimulation Parameter Changes, and Monopolar and Dual-electrode Mode Changes, on Speech Perception in Experienced Adult Cochlear Implant RecipientsResults posted
Results expected
- 2025-08-12Listening Effort in Cochlear Implant UsersResults expected Q2 2028
Recently completed
- 2026-05-01Performance Comparisons With Default Versus Place-based MapsPrimary completion
- 2026-04-16A Pivotal, Prospective, Open-label, Multi-center Study of Safety and Effectiveness of Cochlear Implantation in an Expanded Population of Adults With Bilateral Sensorineural Hearing LossPrimary completion
- 2026-02-28Phase II, Multi-Center, Randomized, Blinded Study Evaluating the Efficacy, Safety and Tolerability of a Single Intratympanic Dose of AC102 Compared to Oral Steroids for the Treatment of Idiopathic Sudden Sensorineural Hearing LossPrimary completion
- 2025-12-01Intracochlear Platelet-rich Fibrin Application in Cochlear ImplantationPrimary completion
- 2025-11-26Remote Support for Cochlear Implant Recipients: Evaluation of the HearCare MED-EL AppCompleted
+3 more in the activity timeline below
Activity timeline11
- 2028-09-30ClinicalVerification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss (Pilot Study)Withdrawn
- 2026-05-01ClinicalPerformance Comparisons With Default Versus Place-based MapsPrimary completion
- 2026-04-16ClinicalA Pivotal, Prospective, Open-label, Multi-center Study of Safety and Effectiveness of Cochlear Implantation in an Expanded Population of Adults With Bilateral Sensorineural Hearing LossPrimary completion
- 2026-02-28ClinicalPhase II, Multi-Center, Randomized, Blinded Study Evaluating the Efficacy, Safety and Tolerability of a Single Intratympanic Dose of AC102 Compared to Oral Steroids for the Treatment of Idiopathic Sudden Sensorineural Hearing LossPrimary completion
- 2026-02-04ClinicalBenefits of Bimodal Streaming for MED-EL Cochlear Implants: Early User Experience With the AudioKey Application and Starkey Hearing AidsResults posted
- 2025-12-31ClinicalEvaluating Design Improvements With SONNET 3 in Experienced Cochlear Implant UsersResults posted
- 2025-12-17ClinicalA Prospective, Single Centre, Single-blinded, Within-subject Investigation, on the Effect of Stimulation Parameter Changes, and Monopolar and Dual-electrode Mode Changes, on Speech Perception in Experienced Adult Cochlear Implant RecipientsResults posted
- 2025-12-01ClinicalIntracochlear Platelet-rich Fibrin Application in Cochlear ImplantationPrimary completion
- 2025-11-26ClinicalRemote Support for Cochlear Implant Recipients: Evaluation of the HearCare MED-EL AppCompleted
- 2025-08-30ClinicalEvaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant SurgeryPrimary completion
Clinical trials
The current development programme across all trial phases.
Clinical programme
18
6
1
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20112021
Most influential
Major themes5
- Computer Simulation1
- Diabetes Mellitus, Type 21
- Hearing Loss1
- Hearing Loss, Sensorineural1
- Models, Biological1
Leading journals2
- Ageing research reviews1
- The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers5
- McAlpine D1
- Ryugo DK1
- Samocha-Bonet D1
- Schaette R1
- Wu B1
Affiliations (unnormalised)2
- Garvan Institute of Medical Research1
- University College London Ear Institute1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.