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Disease
Hearing Loss, Sensorineural
Late-stage therapeutic developmentEmerging research
2
Publications
19
Clinical trials
2021
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Performance Comparisons With Default Versus Place-based Maps
Clinical trial2026-08-18Status changed to Completed · ClinicalTrials.gov
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Moderate
Key developments
- 2 clinical trials expected to report results, the earliest in Q4 2026.
Upcoming Milestones
Major developments
Upcoming trial readoutImportant
Results expected Q4 20282026-07-14
Major trial resultsImportant
Results posted2026-02-04
Clinical MilestonesView all 10Hide
Results posted
Results expected
- 2026-07-14Intracochlear Platelet-rich Fibrin Application in Cochlear ImplantationResults expected Q4 2028
- 2026-04-01A Randomised Controlled Trial to Evaluate the Effectiveness of Spatial-listening Training Delivered Via the Both EARS Training Package (BEARS) in Older Children and Teenagers With Bilateral Cochlear ImplantsResults expected Q4 2026
Recently completed
- 2026-06-24Performance Comparisons With Default Versus Place-based MapsCompleted
- 2026-05-11MED-EL Remote Care Multi-Center Feasibility StudyCompleted
- 2026-04-16A Pivotal, Prospective, Open-label, Multi-center Study of Safety and Effectiveness of Cochlear Implantation in an Expanded Population of Adults With Bilateral Sensorineural Hearing LossPrimary completion
- 2026-02-28Phase II, Multi-Center, Randomized, Blinded Study Evaluating the Efficacy, Safety and Tolerability of a Single Intratympanic Dose of AC102 Compared to Oral Steroids for the Treatment of Idiopathic Sudden Sensorineural Hearing LossPrimary completion
- 2025-12-24A Feasibility, Prospective, Repeated-measures, Within-subject, Interventional Study Investigating the Electrical Categorical Loudness Scaling Using the Mobile Research App in the Home and In-clinic Situation in Experienced Adult Cochlear Implant ParticipantsCompleted
+2 more in the activity timeline below
Activity timeline10
- 2028-09-30ClinicalVerification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss (Pilot Study)Withdrawn
- 2026-07-14ClinicalIntracochlear Platelet-rich Fibrin Application in Cochlear ImplantationResults expected Q4 2028
- 2026-06-24ClinicalPerformance Comparisons With Default Versus Place-based MapsCompleted
- 2026-05-11ClinicalMED-EL Remote Care Multi-Center Feasibility StudyCompleted
- 2026-04-16ClinicalA Pivotal, Prospective, Open-label, Multi-center Study of Safety and Effectiveness of Cochlear Implantation in an Expanded Population of Adults With Bilateral Sensorineural Hearing LossPrimary completion
- 2026-04-01ClinicalA Randomised Controlled Trial to Evaluate the Effectiveness of Spatial-listening Training Delivered Via the Both EARS Training Package (BEARS) in Older Children and Teenagers With Bilateral Cochlear ImplantsResults expected Q4 2026
- 2026-02-28ClinicalPhase II, Multi-Center, Randomized, Blinded Study Evaluating the Efficacy, Safety and Tolerability of a Single Intratympanic Dose of AC102 Compared to Oral Steroids for the Treatment of Idiopathic Sudden Sensorineural Hearing LossPrimary completion
- 2026-02-04ClinicalBenefits of Bimodal Streaming for MED-EL Cochlear Implants: Early User Experience With the AudioKey Application and Starkey Hearing AidsResults posted
- 2025-12-24ClinicalA Feasibility, Prospective, Repeated-measures, Within-subject, Interventional Study Investigating the Electrical Categorical Loudness Scaling Using the Mobile Research App in the Home and In-clinic Situation in Experienced Adult Cochlear Implant ParticipantsCompleted
- 2025-11-26ClinicalRemote Support for Cochlear Implant Recipients: Evaluation of the HearCare MED-EL AppCompleted
Clinical trials
The current development programme across all trial phases.
Clinical programme
19
6
1
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20112021
Most influential
Major themes5
- Computer Simulation1
- Diabetes Mellitus, Type 21
- Hearing Loss1
- Hearing Loss, Sensorineural1
- Models, Biological1
Leading journals2
- Ageing research reviews1
- The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers5
- McAlpine D1
- Ryugo DK1
- Samocha-Bonet D1
- Schaette R1
- Wu B1
Affiliations (unnormalised)2
- Garvan Institute of Medical Research1
- University College London Ear Institute1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.