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Disease
Heredodegenerative Disorders, Nervous System
Clinical development underwayEmerging research
2
Publications
2
Clinical trials
2023
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Research2023-12-20Genes
Astrocytes and disease: a neurodevelopmental perspective.
Research2012-05-01Genes & development
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 1 clinical trial with recent milestones (1 completed or reporting results).
Clinical MilestonesViewHide
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20122023
Most influential
Major themes4
- Heredodegenerative Disorders, Nervous System1
- Mixed Function Oxygenases1
- Neurogenesis1
- Spastic Paraplegia, Hereditary1
Leading journals2
- Genes1
- Genes & development1
Leading researchers8
- Abicht A1
- Arnold P1
- Barres BA1
- Deneen B1
- German A1
- Jukic J1
- Krencik R1
- Laner A1
Affiliations (unnormalised)5
- Center for Rare Diseases (ZSEER)1
- Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research1
- Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)1
- Institute of Functional and Clinical Anatomy1
- Institute of Neuroradiology1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Inherited disorders characterized by progressive atrophy and dysfunction of anatomically or physiologically related neurologic systems.
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.