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Disease

Hypercapnia

Active therapeutic pipelineEmerging research
MeSHHypercapnia
2
Publications
7
Clinical trials
2023
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q3 2026.
Upcoming Milestones
Major developments
Upcoming trial readoutWorth watching
Applied Physiology of Oxygen Toxicity: Mechanisms in Humans
Results expected Q3 20262025-10-23
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

6 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
7
All trials
1
Active
0
Late-stage
5
Completed
Recruiting

Applied Physiology of Oxygen Toxicity: Mechanisms in Humans

N/A · Recruiting · Duke University
Recently completed

Influence of Caffeine on Psychomotor Vigilance and Carbon Dioxide Tolerance During Graded Hypercapnia

N/A · Completed · United States Army Research Institute of Environmental Medicine

Clinical Study to Investigate the Effect of Administration of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation

Phase 1 · Completed · Food and Drug Administration (FDA)

Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on Ventilation

Phase 1 · Completed · Food and Drug Administration (FDA)

A Study of Changes in Blood Gases, Disturbance of Breath During Sleep and Cardiovascular Co-morbidity in Patients With COPD in Different Stages of the Disease, and the Effect of Alcohol, Supplementary Oxygen and Zopiclone on These Changes.

N/A · Completed · LHL Helse

Application of Nasal Cannula With Oxygen Versus Air During Eye Surgery Under Local Anaesthetic

Phase 1 · Completed · University of Malaya

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20222023
Major themes2
  • Hypercapnia1
  • Out-of-Hospital Cardiac Arrest1
Leading journals2
  • Resuscitation1
  • The Journal of experimental medicine1
Leading researchers8
  • Andersen GØ1
  • Balázsfi D1
  • Baranyi M1
  • Bellomo R1
  • Benyó Z1
  • Brás AR1
  • Császár E1
  • Cserép C1
Affiliations (unnormalised)6
  • "Momentum" Laboratory of Neuroimmunology1
  • Albert Szent-Györgyi Medical School1
  • Austin Hospital1
  • Hungarian Centre of Excellence for Molecular Medicine1
  • Institute of Psychiatry and Neurosciences of Paris1
  • Institute of Translational Medicine1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Identifiers
MeSHHypercapnia
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.