Back to discover
Disease

Hypokalemic periodic paralysis

Late-stage therapeutic development
Also known as HKPP, HOKPP, HypoPP, Westphall disease+5 more

HKPP, HOKPP, HypoPP, Westphall disease, familial hypokalemic periodic paralysis, familial periodic paralysis (& [hypokalaemic]), hypokalemic familial periodic paralysis, periodic hypokalemic paralysis, periodic paralysis I.

3
Clinical trials
4
Associated genes
1
Related proteins

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

No activity recorded in this window. Try a wider timeframe.

Clinical trials

3 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
3
All trials
0
Active
2
Late-stage
2
Completed
Late-stage studies
Recently completed

Associated genes

4 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

An autosomal dominant familial disorder characterized by recurrent episodes of skeletal muscle weakness associated with falls in serum potassium levels. The condition usually presents in the first or second decade of life with attacks of trunk and leg paresis during sleep or shortly after awakening. Symptoms may persist for hours to days and generally are precipitated by exercise or a meal high in carbohydrates. (Adams et al., Principles of Neurology, 6th ed, p1483)

Synonyms

HKPP, HOKPP, HypoPP, Westphall disease, familial hypokalemic periodic paralysis, familial periodic paralysis (& [hypokalaemic]), hypokalemic familial periodic paralysis, periodic hypokalemic paralysis, periodic paralysis I

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.