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Disease

Hypoxia, Brain

Late-stage therapeutic developmentEmerging research
1
Publications
4
Clinical trials
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q4 2027.
Major developments
Upcoming trial readoutImportant
Results expected Q4 20272026-05-01
Clinical Milestones1View

Clinical trials

4 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes2
  • Dendritic Spines1
  • Neurons1
Leading journals1
  • Cellular and molecular neurobiology1
Leading researchers7
  • Cui C1
  • Jiang X1
  • Li C1
  • Lin Z1
  • Ni Q1
  • Wang Y1
  • Wei Y1
Affiliations (unnormalised)2
  • Hydrogen Medical Research Center1
  • Research Center for Translational Medicine & Key Laboratory of Arrhythmias of the Ministry of Education of China1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.