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Disease

immunoglobulin G4-related sclerosing disease

Also known as IgG4-RD, IgG4-related disease, IgG4-related sclerosing disease, IgG4-related systemic disease+10 more

IgG4-RD, IgG4-related disease, IgG4-related sclerosing disease, IgG4-related systemic disease, IgG4-associated disease, IgG4-positive multiorgan lymphoproliferative syndrome, IgG4-related autoimmune disease, IgG4-related systemic sclerosing disease, IgG4-syndrome, hyper-IgG4 disease, multifocal fibrosclerosis, multifocal idiopathic fibrosclerosis, systemic IgG4-related plasmacytic syndrome, systemic IgG4-related sclerosing syndrome.

12
Associated genes
1
Related proteins
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

A Phase IIa, Single-Site, Open-Label Study of Efgartigimod in Patients With IgG4-Related Disease

Clinical trial2026-07-23Status changed to Active, not recruiting · ClinicalTrials.gov

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Synonyms

IgG4-RD, IgG4-related disease, IgG4-related sclerosing disease, IgG4-related systemic disease, IgG4-associated disease, IgG4-positive multiorgan lymphoproliferative syndrome, IgG4-related autoimmune disease, IgG4-related systemic sclerosing disease, IgG4-syndrome, hyper-IgG4 disease, multifocal fibrosclerosis, multifocal idiopathic fibrosclerosis, systemic IgG4-related plasmacytic syndrome, systemic IgG4-related sclerosing syndrome

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.