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Disease

Infant, Premature, Diseases

Late-stage therapeutic developmentEmerging research
MeSHInfant, Premature, Diseases
1
Publications
8
Clinical trials
2025
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial with recent milestones (1 completed or reporting results).
Clinical Milestones1View
Results posted 1
Activity timeline1

Clinical trials

8 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
8
All trials
2
Active
5
Late-stage
6
Completed
Late-stage studies

Exogenous Surfactant in Very Preterm Neonates Presenting With Severe Respiratory Distress in Prevention of Bronchopulmonary Dysplasia

Phase 4 · Completed · Jean Michel Hascoet

A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm Infants

Phase 3 · Completed · Lingfen Xu, MD

Fish Oil Lipid Emulsion for the Treatment of Parenteral-Nutrition-Associated Liver Disease in Infants

Phase 2/3 · Completed · University of Oklahoma

Efficacy and Safety of Continuous Infusion of Fentanyl for Pain Control in Preterm Newborn on Mechanical Ventilation

Phase 3 · Completed · IRCCS Azienda Ospedaliero-Universitaria di Bologna

Safety During Use of Paediatric Triple Chamber Bag Formulas, Administered IV at a Weight Dependant Dose During 5 Consecutive Days, in Paediatric Patients up to 18 Years Requiring Parenteral Nutrition.

Phase 3 · Completed · Baxter Healthcare Corporation
Recruiting

Dose-finding for Dobutamine During Transitional Circulation in the Very Preterm Infant

Phase 1/2 · Recruiting · Instituto de Investigación Hospital Universitario La Paz
Recently completed

Exogenous Surfactant in Very Preterm Neonates Presenting With Severe Respiratory Distress in Prevention of Bronchopulmonary Dysplasia

Phase 4 · Completed · Jean Michel Hascoet

Fish Oil Lipid Emulsion for the Treatment of Parenteral-Nutrition-Associated Liver Disease in Infants

Phase 2/3 · Completed · University of Oklahoma

Serum Concentrations of Vascular Endothelial Growth Factor in Infants Treated With Ranibizumab for Retinopathy of Prematurity

N/A · Completed · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm Infants

Phase 3 · Completed · Lingfen Xu, MD

Efficacy and Safety of Continuous Infusion of Fentanyl for Pain Control in Preterm Newborn on Mechanical Ventilation

Phase 3 · Completed · IRCCS Azienda Ospedaliero-Universitaria di Bologna

Safety During Use of Paediatric Triple Chamber Bag Formulas, Administered IV at a Weight Dependant Dose During 5 Consecutive Days, in Paediatric Patients up to 18 Years Requiring Parenteral Nutrition.

Phase 3 · Completed · Baxter Healthcare Corporation

Research activity

1 paper

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Invited Mini Review Metabolic Bone Disease of Prematurity: Overview and Practice Recommendations.

Hormone research in paediatrics · 2025 · 11 cites
Recent publications

Invited Mini Review Metabolic Bone Disease of Prematurity: Overview and Practice Recommendations.

Hormone research in paediatrics · 2025 · 11 cites
Major themes2
  • Bone Diseases, Metabolic1
  • Infant, Premature, Diseases1
Leading journals1
  • Hormone research in paediatrics1
Leading researchers8
  • Ashraf AP1
  • Bowden SA1
  • Calabria A1
  • Diaz-Thomas A1
  • DiMeglio LA1
  • Grover M1
  • Krishnan S1
  • Miller JL1
Affiliations (unnormalised)6
  • Indiana University School of Medicine1
  • Nationwide Children's Hospital/The Ohio State University1
  • Northwestern University Feinberg School of Medicine1
  • Stanford School of Medicine1
  • The Children's Hospital of Philadelphia1
  • University of Alabama at Birmingham1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Diseases that occur in PREMATURE INFANTS.

Identifiers
MeSHInfant, Premature, Diseases
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.