Intermittent Claudication
Recent clinical, regulatory, research and industry developments relating to this disease.
Epidemiology of peripheral artery disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 2 clinical trials expected to report results, the earliest in Q1 2027.
Clinical MilestonesViewHide
- 2026-04-21Metformin BenefIts Lower Extremities With Intermittent Claudication (MOBILE_IC)Results expected Q1 2027
- 2025-08-26IMProving Mobility After revasCularizaTion in Peripheral Artery Disease: The IMPACT PAD TrialResults expected Q1 2032
- 2026-04-21ClinicalMetformin BenefIts Lower Extremities With Intermittent Claudication (MOBILE_IC)Results expected Q1 2027
- 2025-08-26ClinicalIMProving Mobility After revasCularizaTion in Peripheral Artery Disease: The IMPACT PAD TrialResults expected Q1 2032
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes1
- Ankle Brachial Index1
Leading journals1
- Circulation research1
Leading researchers2
- Aboyans V1
- Criqui MH1
Affiliations (unnormalised)1
- University of California1
Reference
Authoritative identity, definition & identifiers.
A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.