Back to discover
Disease
Intestinal Neoplasms
Late-stage therapeutic developmentEmerging researchRising momentum
3
Publications
7
Clinical trials
2024
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Research2024-04-29CA: a cancer journal for clinicians
Research2015-03-31Endoscopy
Intestinal goblet cells and mucins in health and disease: recent insights and progress.
Research2010-10-01Current gastroenterology reports
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 2 clinical trials expected to report results, the earliest in Q4 2026.
Upcoming Milestones
- Q4 2026A Multinational, Randomized, Phase III Study of FOLFIRI With/Without Bevacizumab Versus Irinotecan With/Without Bevacizumab As Second-line Therapy in Patients With Metastatic Colorectal Cancer
- Q1 2030AN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH METASTATIC COLORECTAL CANCER
Major developments
Upcoming trial readoutHigh impact
Results expected Q1 20302026-07-06
Upcoming trial readoutHigh impact
Results expected Q4 20262026-06-05
Clinical MilestonesViewHide
Results expected
- 2026-07-06AN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH METASTATIC COLORECTAL CANCERResults expected Q1 2030
- 2026-06-05A Multinational, Randomized, Phase III Study of FOLFIRI With/Without Bevacizumab Versus Irinotecan With/Without Bevacizumab As Second-line Therapy in Patients With Metastatic Colorectal CancerResults expected Q4 2026
Activity timeline3
- 2026-07-06ClinicalAN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH METASTATIC COLORECTAL CANCERResults expected Q1 2030
- 2026-06-05ClinicalA Multinational, Randomized, Phase III Study of FOLFIRI With/Without Bevacizumab Versus Irinotecan With/Without Bevacizumab As Second-line Therapy in Patients With Metastatic Colorectal CancerResults expected Q4 2026
- 2025-12-01ClinicalA Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemotherapy Combined With Lateral Lymph Node Dissection in Low- and Medium-lying Rectal Cancer With Lateral Lymph Node MetastasisCompleted
Clinical trials
The current development programme across all trial phases.
Clinical programme
7
2
3
4
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20102024
Most influential
Recent publications
Major themes7
- Capsule Endoscopy1
- Double-Balloon Enteroscopy1
- Intestinal Neoplasms1
- Neoplasm Staging1
- Neuroendocrine Tumors1
- Pancreatic Neoplasms1
- Stomach Neoplasms1
Leading journals3
- CA: a cancer journal for clinicians1
- Current gastroenterology reports1
- Endoscopy1
Leading researchers8
- Adler SN1
- Albert J1
- Anaya DA1
- Asare EA1
- Baltes P1
- Barbaro F1
- Bellizzi AM1
- Bergsland E1
Affiliations (unnormalised)6
- Catholic University1
- Centre Hospitalier Lyon Sud1
- Centro Hospitalar do Alto Ave1
- Chaim Sheba Medical Center1
- Clinical Psychology Unit1
- Duke University Medical Center1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Tumors or cancer of the INTESTINES.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.