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Disease
Iron Deficiencies
Late-stage therapeutic developmentEmerging research
2
Publications
10
Clinical trials
2024
Latest publication
Current focus
Therapeutic developmentInflammation & immunityMetabolic & lifestyle factors
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Effects of Iron Status on Adaptive Immunity and Vaccine Efficacy: A Review.
Research2024-05-08Advances in nutrition (Bethesda, Md.)
Approval: Feraccru (EMA)
Regulatory2016-02-18EMA
Nutrition and brain development in early life.
Research2014-03-28Nutrition reviews
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 4 clinical trials expected to report results, the earliest in Q4 2026.
Upcoming Milestones
- Q4 2026A Phase 1, 3-Part, Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Oral Doses of CTX001 in Healthy Adult Participants.
- Q4 2026Study on Supplement of Intravenous Ferric Derisomaltose to Prevent Anemia and Improve the Quality of Life in Obese Patients With Iron Deficiency.
- Q2 2028Phase IV, Open-label, Randomized Clinical Trial on the Effect of Intravenous Iron on Quality of Life in Elderly Patients With Acute Coronary Syndrome
- Q2 2029Long-term Outcomes Sub-Study of Preoperative Combined Iron Therapy in Anemic Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial
Major developments
Upcoming trial readoutHigh impact
Results expected Q2 20282026-03-24
Upcoming trial readoutImportant
Results expected Q4 20262026-06-12
Clinical MilestonesViewHide
Results expected
- 2026-06-12A Phase 1, 3-Part, Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Oral Doses of CTX001 in Healthy Adult Participants.Results expected Q4 2026
- 2026-04-13Long-term Outcomes Sub-Study of Preoperative Combined Iron Therapy in Anemic Patients Undergoing Cardiac Surgery: A Randomized Controlled TrialResults expected Q2 2029
- 2026-03-24Phase IV, Open-label, Randomized Clinical Trial on the Effect of Intravenous Iron on Quality of Life in Elderly Patients With Acute Coronary SyndromeResults expected Q2 2028
- 2025-11-19Study on Supplement of Intravenous Ferric Derisomaltose to Prevent Anemia and Improve the Quality of Life in Obese Patients With Iron Deficiency.Results expected Q4 2026
Recently completed
- 2025-11-18Optimizing Dosing Strategies in Oral Iron SupplementationCompleted
Activity timeline5
- 2026-06-12ClinicalA Phase 1, 3-Part, Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Oral Doses of CTX001 in Healthy Adult Participants.Results expected Q4 2026
- 2026-04-13ClinicalLong-term Outcomes Sub-Study of Preoperative Combined Iron Therapy in Anemic Patients Undergoing Cardiac Surgery: A Randomized Controlled TrialResults expected Q2 2029
- 2026-03-24ClinicalPhase IV, Open-label, Randomized Clinical Trial on the Effect of Intravenous Iron on Quality of Life in Elderly Patients With Acute Coronary SyndromeResults expected Q2 2028
- 2025-11-19ClinicalStudy on Supplement of Intravenous Ferric Derisomaltose to Prevent Anemia and Improve the Quality of Life in Obese Patients With Iron Deficiency.Results expected Q4 2026
- 2025-11-18ClinicalOptimizing Dosing Strategies in Oral Iron SupplementationCompleted
Clinical trials
The current development programme across all trial phases.
Clinical programme
10
5
3
2
Late-stage studies
Recruiting
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20142024
Most influential
Major themes5
- Adaptive Immunity1
- Iron1
- Iron Deficiencies1
- Nutritional Status1
- Vaccine Efficacy1
Leading journals2
- Advances in nutrition (Bethesda, Md.)1
- Nutrition reviews1
Leading researchers4
- Dewey KG1
- Drakesmith H1
- Prado EL1
- Stoffel NU1
Affiliations (unnormalised)2
- Medical Research Council Weatherall Institute of Molecular Medicine1
- University of California at Davis1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Deficient amounts of iron in the body as a result of blood loss, diets deficient in iron, or an iron uptake or storage disorder.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.