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Disease

Keratitis, Herpetic

Late-stage therapeutic developmentEmerging research
1
Publications
2
Clinical trials
2023
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

In vivo CRISPR gene editing in patients with herpetic stromal keratitis.

Research2023-08-31Molecular therapy : the journal of the American Society of Gene Therapy

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
2
All trials
0
Active
1
Late-stage
1
Completed
Late-stage studies

Herpetic Eye Disease Study (HEDS) II

Phase 3 · Completed · National Eye Institute (NEI)
Recently completed

Herpetic Eye Disease Study (HEDS) II

Phase 3 · Completed · National Eye Institute (NEI)

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

In vivo CRISPR gene editing in patients with herpetic stromal keratitis.

Molecular therapy : the journal of the American Society of Gene Therapy · 2023 · 43 cites
Recent publications

In vivo CRISPR gene editing in patients with herpetic stromal keratitis.

Molecular therapy : the journal of the American Society of Gene Therapy · 2023 · 43 cites
Major themes2
  • Herpesvirus 1, Human1
  • Keratitis, Herpetic1
Leading journals1
  • Molecular therapy : the journal of the American Society of Gene Therapy1
Leading researchers8
  • Cai Y1
  • Hong J1
  • Le H1
  • Ling S1
  • Paludan SR1
  • Tian L1
  • Wei A1
  • Xu J1
Affiliations (unnormalised)3
  • Aarhus University1
  • and ENT Hospital1
  • Key Laboratory of Systems Biomedicine (Ministry of Education)1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed)

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.