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Disease

Kidney Calculi

Late-stage therapeutic developmentEmerging research
MeSHKidney Calculi
2
Publications
10
Clinical trials
2023
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q1 2027.
Upcoming Milestones
Clinical Milestones2View
Results posted 1
Results expected 1
Activity timeline2

Clinical trials

9 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
10
All trials
2
Active
7
Late-stage
6
Completed
Late-stage studies

Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)

Phase 4 · Completed · Northwestern University

Study of Ketorolac Versus Opioid for Pain After Endoscopy (SKOPE): A Double-blinded Randomized Control Trial Comparing Outpatient Analgesic Efficacy of NSAIDs and Opioids in Patients Undergoing Ureteroscopy for Kidney Stones

Phase 4 · Completed · The Cleveland Clinic

The Effect of Allopurinol on Malondialdehyde, Nitric Oxide, Kidney Injury Molecule-1 Urine Levels, Resistive Index and Renal Elastography in Kidney Stone Patients After Extra Corporeal Shockwave Lithotripsy

Phase 4 · Completed · Sanglah General Hospital

A Randomized Controlled Trial for Evaluating Protective Effects of Antioxidants (Selenium and Vitamins A, C and E), Calcium Channel Blocker (Verapamil) and Angiotensin Receptor Blocker (Losartan) Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury

Phase 4 · Completed · Mansoura University

Total Intravenous Anaesthesia Using Remifentanil In Extracorporeal Shock Wave Lithotripsy (ESWL). Comparison of Two Dosages.

Phase 4 · Completed · University of Roma La Sapienza

Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis

Phase 4 · Completed · Ouiheng International Healthcare Co., Ltd
Recently completed

Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)

Phase 4 · Completed · Northwestern University

Study of Ketorolac Versus Opioid for Pain After Endoscopy (SKOPE): A Double-blinded Randomized Control Trial Comparing Outpatient Analgesic Efficacy of NSAIDs and Opioids in Patients Undergoing Ureteroscopy for Kidney Stones

Phase 4 · Completed · The Cleveland Clinic

The Effect of Allopurinol on Malondialdehyde, Nitric Oxide, Kidney Injury Molecule-1 Urine Levels, Resistive Index and Renal Elastography in Kidney Stone Patients After Extra Corporeal Shockwave Lithotripsy

Phase 4 · Completed · Sanglah General Hospital

A Randomized Controlled Trial for Evaluating Protective Effects of Antioxidants (Selenium and Vitamins A, C and E), Calcium Channel Blocker (Verapamil) and Angiotensin Receptor Blocker (Losartan) Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury

Phase 4 · Completed · Mansoura University

Total Intravenous Anaesthesia Using Remifentanil In Extracorporeal Shock Wave Lithotripsy (ESWL). Comparison of Two Dosages.

Phase 4 · Completed · University of Roma La Sapienza

Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis

Phase 4 · Completed · Ouiheng International Healthcare Co., Ltd

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes3
  • Kidney Calculi2
  • Diabetes Mellitus, Type 21
  • Kidney Medulla1
Leading journals2
  • Frontiers in endocrinology1
  • Nature communications1
Leading researchers8
  • Barwinska D1
  • Bowen WS1
  • Canela VH1
  • Chen H1
  • Chen J1
  • Chen Z1
  • Cheng YH1
  • Coe FL1
Affiliations (unnormalised)6
  • Center for Diabetes and Metabolic Diseases1
  • Indiana University School of Medicine1
  • Indianapolis VA Medical Center1
  • National Clinical Research Center for Geriatric Disorders1
  • San Diego Institute of Science1
  • University of Chicago1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.

Identifiers
MeSHKidney Calculi
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.