Back to discover
Disease

Latent Autoimmune Diabetes in Adults

Late-stage therapeutic developmentEmerging research
MeSHLatent Autoimmune Diabetes in Adults
2
Publications
24
Clinical trials
1
Related conditions
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Moderate
Key developments
  • 5 clinical trials expected to report results, the earliest in Q2 2027.
Upcoming Milestones
Clinical Milestones9View all 9
Results posted 2
Results expected 5
Recently completed 2
+1 more in the activity timeline below
Activity timeline9

Clinical trials

17 sponsors · 4 new · 2 completed in the last 12 months (net +4)

The current development programme across all trial phases.

Clinical programme
24
All trials
6
Active
18
Late-stage
6
Completed
Late-stage studies

Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes

Phase 3 · Recruiting · Steno Diabetes Center Copenhagen

Effectiveness and Safety of Sotagliflozin in Slowing Kidney Function Decline in Persons With Type 1 Diabetes and Moderate to Severe Diabetic Kidney Disease

Phase 3 · Recruiting · Alessandro Doria

Fully Closed-Loop Glucose Control in Adults With Type 1 Diabetes Using Tirzepatide: a Randomized, Multi-center, Open-label, Non-inferiority, Parallel Trial

Phase 2/3 · Recruiting · McGill University Health Centre/Research Institute of the McGill University Health Centre

A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating the Efficacy and Safety of Dimethyl Fumarate in Preserving Islet β-Cell Function in Patients With Type 1 Diabetes Mellitus

Phase 3 · Recruiting · Nanjing Medical University

Non-Randomized, Parallel-Controlled, Single-Center, Open-Label Clinical Trial Evaluating the Efficacy and Safety of Dimethyl Fumarate in Preserving Pancreatic β-Cell Function in Adults With Type 1 Diabetes

Phase 2/3 · Recruiting · Nanjing Medical University

Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D)

Phase 4 · Recruiting · Ohio State University
Recruiting

Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes

Phase 3 · Recruiting · Steno Diabetes Center Copenhagen

Effectiveness and Safety of Sotagliflozin in Slowing Kidney Function Decline in Persons With Type 1 Diabetes and Moderate to Severe Diabetic Kidney Disease

Phase 3 · Recruiting · Alessandro Doria

Fully Closed-Loop Glucose Control in Adults With Type 1 Diabetes Using Tirzepatide: a Randomized, Multi-center, Open-label, Non-inferiority, Parallel Trial

Phase 2/3 · Recruiting · McGill University Health Centre/Research Institute of the McGill University Health Centre

A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating the Efficacy and Safety of Dimethyl Fumarate in Preserving Islet β-Cell Function in Patients With Type 1 Diabetes Mellitus

Phase 3 · Recruiting · Nanjing Medical University

Non-Randomized, Parallel-Controlled, Single-Center, Open-Label Clinical Trial Evaluating the Efficacy and Safety of Dimethyl Fumarate in Preserving Pancreatic β-Cell Function in Adults With Type 1 Diabetes

Phase 2/3 · Recruiting · Nanjing Medical University

Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D)

Phase 4 · Recruiting · Ohio State University
Recently completed

Effect of Sodium-Glucose Cotransporter (SGLT) 2 Inhibitors on Diabetic Nephropathy Progression in Adolescents With Type 1 Diabetes Mellitus

Phase 2/3 · Completed · Ain Shams University

A Parallel-group, Randomized, Prospective, Interventional, Double-blind, Multicenter Global Phase 3 Study to Investigate the Efficacy and Safety of Finerenone Versus Placebo, in Addition to Standard of Care, in Participants With Chronic Kidney Disease and Type 1 Diabetes

Phase 3 · Completed · Bayer

A Phase 3, Randomized, Open-Label, Multicenter, Active-controlled Trial Comparing Efficacy and Safety of THDB0206 Injection With Insulin Lispro Injection Combined With Insulin Glargine Injection U-100 in Chinese Participants With Type 1 Diabetes

Phase 3 · Completed · Tonghua Dongbao Pharmaceutical Co.,Ltd

Phase 3, Single-administration, Open-label Trial to Assess the Efficacy, Safety, PK, and PD of Dasiglucagon When Administered as a Rescue Therapy for Severe Hypoglycemia in Pediatric Patients Below 6 Years of Age With Type 1 Diabetes (T1D)

Phase 3 · Completed · Zealand Pharma

Human Versus Analogue Insulin for Youth With Type 1 Diabetes in Low-Resource Settings: A Randomized Controlled Trial

Phase 4 · Completed · Jing Luo

A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients

Phase 3 · Completed · Northwestern University

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20202024
Major themes7
  • Diabetes Mellitus, Type 21
  • Diabetic Ketoacidosis1
  • Glucagon-Like Peptide-1 Receptor Agonists1
  • Glucagon-Like Peptides1
  • Hypoglycemic Agents1
  • Immunoglobulin Fc Fragments1
  • Recombinant Fusion Proteins1
Leading journals2
  • Diabetes1
  • Medicine1
Leading researchers8
  • Buzzetti R1
  • Leslie RD1
  • Ma Y1
  • Mauricio D1
  • Pietropaolo M1
  • Pozzilli P1
  • Tuomi T1
  • Wang X1
Affiliations (unnormalised)6
  • Abdominal Center1
  • Affiliated Hospital of Hebei University1
  • Blizard Institute1
  • Campus Bio-Medico University1
  • Diabetes Research Center1
  • Hebei University School of Basic Medical Sciences1

Related conditions

1 match

Diseases frequently studied alongside this one. Number shows shared papers.

Diabetes Mellitus, Type 22

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Autoimmune diabetes in adults with slowly progressive PANCREATIC BETA CELL failure and the presence of circulating autoantibodies to PANCREATIC ISLETS cell antigens.

Identifiers
MeSHLatent Autoimmune Diabetes in Adults
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.