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Disease
Leiomyoma
Late-stage therapeutic developmentEmerging research
2
Publications
15
Clinical trials
2024
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Research2024-02-07Nature communications
Research2023-07-10Nature communications
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 2 clinical trials expected to report results, the earliest in Q4 2027.
Upcoming Milestones
Major developments
Upcoming trial readoutHigh impact
Results expected Q3 20282026-07-22
Major trial resultsHigh impact
Results posted2026-01-07
Clinical MilestonesViewHide
Results posted
Results expected
- 2026-07-22Letrozole for Treatment of Uterine Fibroids: A Randomized, Placebo-Controlled TrialResults expected Q3 2028
- 2026-03-18Transcutaneous Electrical Acupoint Stimulation Combined With Triple Antiemetic Drugs for Postoperative Nausea and Vomiting in High-Risk Patients: A Multicenter Randomized Controlled TrialResults expected Q4 2027
Recently completed
Activity timeline5
- 2026-07-31ClinicalA Double-blinded, Phase II, Randomized Control Trial to Study the Effects of Simvastatin in Patients With Uterine LeiomyomaPrimary completion
- 2026-07-22ClinicalLetrozole for Treatment of Uterine Fibroids: A Randomized, Placebo-Controlled TrialResults expected Q3 2028
- 2026-06-30ClinicalFibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea (FRIEND)Primary completion
- 2026-03-18ClinicalTranscutaneous Electrical Acupoint Stimulation Combined With Triple Antiemetic Drugs for Postoperative Nausea and Vomiting in High-Risk Patients: A Multicenter Randomized Controlled TrialResults expected Q4 2027
- 2026-01-07ClinicalIntra-Arterial Dexamethasone for the Alleviation of Pain and Postembolization Syndrome Following Uterine Artery EmbolizationResults posted
Clinical trials
The current development programme across all trial phases.
Clinical programme
15
4
11
6
Late-stage studies
Recruiting
Recently completed
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Publications over time
20232024
Most influential
Major themes2
- Leiomyoma2
- Genome-Wide Association Study1
Leading journals1
- Nature communications2
Leading researchers8
- Abdula F2
- Adli M2
- Buyukcelebi K2
- Duval AJ2
- Elkafas H2
- Seker-Polat F2
- Bulun SE1
- Chen X1
Affiliations (unnormalised)3
- Robert Lurie Comprehensive Cancer Center2
- Feinberg School of Medicine Northwestern University1
- Northwestern University Feinberg School of Medicine1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.