Disease

Leptospirosis

Late-stage therapeutic developmentEmerging research

MeSHLeptospirosis

Publications

Clinical trials

2013

Latest publication

Latest activity

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Recent clinical, regulatory, research and industry developments relating to this disease.

Extreme water-related weather events and waterborne disease.

Research2012-08-09Epidemiology and infection

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low

Key developments

1 clinical trial expected to report results, the earliest in Q1 2027.

Upcoming Milestones

Q1 2027Decreasing Leptospirosis Emergence Through Prognosis and Treatment Optimization (DeLEPTO) Project 1: Preventive Strategies for Early and Late Complications of Leptospirosis

Major developments

Upcoming trial readoutImportant

Decreasing Leptospirosis Emergence Through Prognosis and Treatment Optimization (DeLEPTO) Project 1: Preventive Strategies for Early and Late Complications of Leptospirosis

Results expected Q1 20272026-04-13

Clinical Milestones1View

Results expected 1

2026-04-13Decreasing Leptospirosis Emergence Through Prognosis and Treatment Optimization (DeLEPTO) Project 1: Preventive Strategies for Early and Late Complications of LeptospirosisResults expected Q1 2027

Activity timeline1

2026-04-13ClinicalDecreasing Leptospirosis Emergence Through Prognosis and Treatment Optimization (DeLEPTO) Project 1: Preventive Strategies for Early and Late Complications of LeptospirosisResults expected Q1 2027

Clinical trials

2 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme

All trials

Active

Late-stage

Completed

Late-stage studies

An Open Randomized Controlled Trial of Desmopressin, and Dexamethasone as Adjunctive Therapy in Patients With Pulmonary Hemorrhage Associated With Leptospirosis

Phase 2/3 · Terminated · Mahidol University

Recruiting

Decreasing Leptospirosis Emergence Through Prognosis and Treatment Optimization (DeLEPTO) Project 1: Preventive Strategies for Early and Late Complications of Leptospirosis

Phase 2 · Recruiting · National Kidney and Transplant Institute, Philippines

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Extreme water-related weather events and waterborne disease.

Epidemiology and infection · 2013 · 200 cites

Recent publications

Extreme water-related weather events and waterborne disease.

Epidemiology and infection · 2013 · 200 cites

Major themes2

Disease Outbreaks1
Weather1

Leading journals1

Epidemiology and infection1

Leading researchers5

Cann KF1
Kay D1
Salmon RL1
Thomas DR1
Wyn-Jones AP1

Affiliations (unnormalised)1

Communicable Disease Surveillance Centre1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Infections with bacteria of the genus LEPTOSPIRA.

Identifiers

MeSHLeptospirosis

References & data sources

Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
Related entities are derived from literature co-mention (studied together) — associative, not causal.