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Disease
Lymphohistiocytosis, Hemophagocytic
Late-stage therapeutic developmentEmerging research
1
Publications
2
Clinical trials
2023
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome.
Research2023-03-09Transplantation and cellular therapy
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 1 clinical trial with recent milestones.
Major developments
Major clinical milestoneImportant
Primary completion2026-06-27
Clinical MilestonesViewHide
Recently completed
- 2026-06-27Prospective Single-Arm Clinical Trial of Golidocitinib Monotherapy for Hemophagocytic Lymphohistiocytosis.Primary completion
Activity timeline1
- 2026-06-27ClinicalProspective Single-Arm Clinical Trial of Golidocitinib Monotherapy for Hemophagocytic Lymphohistiocytosis.Primary completion
Clinical trials
The current development programme across all trial phases.
Clinical programme
2
1
1
1
Late-stage studies
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes2
- Lymphohistiocytosis, Hemophagocytic1
- Neurotoxicity Syndromes1
Leading journals1
- Transplantation and cellular therapy1
Leading researchers8
- Ahmed S1
- Berliner N1
- Frank MJ1
- Frey NV1
- Frigault MJ1
- Henter JI1
- Hill JA1
- Hines MR1
Affiliations (unnormalised)6
- Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania1
- Brigham and Women's Hospital1
- Cancer and Blood Disorders Institute1
- Cancer Center1
- Center for Cancer Research1
- Dana-Farber Cancer Institute1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
A group of related disorders characterized by LYMPHOCYTOSIS; HISTIOCYTOSIS; and hemophagocytosis. The two major forms are familial and reactive.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.