Lymphohistiocytosis, Hemophagocytic
Recent clinical, regulatory, research and industry developments relating to this disease.
Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial with recent milestones.
Clinical MilestonesViewHide
- 2026-06-27Prospective Single-Arm Clinical Trial of Golidocitinib Monotherapy for Hemophagocytic Lymphohistiocytosis.Primary completion
- 2026-06-27ClinicalProspective Single-Arm Clinical Trial of Golidocitinib Monotherapy for Hemophagocytic Lymphohistiocytosis.Primary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes2
- Lymphohistiocytosis, Hemophagocytic1
- Neurotoxicity Syndromes1
Leading journals1
- Transplantation and cellular therapy1
Leading researchers8
- Ahmed S1
- Berliner N1
- Frank MJ1
- Frey NV1
- Frigault MJ1
- Henter JI1
- Hill JA1
- Hines MR1
Affiliations (unnormalised)6
- Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania1
- Brigham and Women's Hospital1
- Cancer and Blood Disorders Institute1
- Cancer Center1
- Center for Cancer Research1
- Dana-Farber Cancer Institute1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
A group of related disorders characterized by LYMPHOCYTOSIS; HISTIOCYTOSIS; and hemophagocytosis. The two major forms are familial and reactive.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.