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Disease

Mouth Diseases

Late-stage therapeutic developmentEmerging research
MeSHMouth Diseases
2
Publications
4
Clinical trials
12
Associated genes
3
Related proteins
2024
Latest publication
Current focus
Osteopontin biologySomatostatin biologyTherapeutic developmentInflammation & immunity
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

4 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
4
All trials
0
Active
2
Late-stage
4
Completed
Recently completed

The Impact of Ginger Mouthwash on the Pregnant Women With Stress and Gingivitis by Measuring Different Salivary Biomarkers Levels (Randomized Clinical Trial)

Phase 2 · Completed · Al-Mustansiriyah University

The Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide in the Management of Dental Biofilm-induced Gingivitis: a 14 Days Randomized Clinical Trial

Phase 3 · Completed · University of Baghdad

Peri-implantitis - Regenerative Treatment With Enamel Matrix Derivative (EMD). Clinical Effects, Microbial Profiles and Molecular Mechanisms. A Randomised Controlled Pilot Study.

Phase 4 · Completed · Catrine Isehed

Phase II, Multicenter, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study of the Effects of RK-0202 on Oral Mucositis in Patients Receiving Radiation Therapy for Tumors of the Oral Cavity, Oropharynx, Nasopharynx, Salivary Glands or Supraglottic Region

Phase 2 · Completed · RxKinetix

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20222024
Major themes6
  • Academic Medical Centers1
  • Dental Caries1
  • Immune Checkpoint Inhibitors1
  • Microbiota1
  • Mouth Diseases1
  • Periodontal Diseases1
Leading journals2
  • Head & neck1
  • International journal of oral science1
Leading researchers8
  • Al-Eryani K1
  • Cheng L1
  • Epstein JB1
  • Li Y1
  • Monreal AV1
  • Peng X1
  • Ren B1
  • Tang C1
Affiliations (unnormalised)6
  • City of Hope Comprehensive Cancer Center1
  • Herbert Wertheim College of Medicine1
  • Herman Ostrow School of Dentistry1
  • Miami Cancer Institute1
  • State Key Laboratory of Oral Diseases1
  • University of California1

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

C22orf310.34TBX220.33ARL4C0.32IL190.32ZNF6440.32CSNK2A10.28TRIP120.26CASD10.26ACOX30.26MICOS100.26PTDSS10.25SST0.25

Disease biology

3 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Somatostatinvia SST0.25Osteopontinvia SPP10.21Beta-arrestin-1via ARRB10.14

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Diseases involving the MOUTH.

Identifiers
MeSHMouth Diseases
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.