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Disease

Neck Pain

Late-stage therapeutic developmentEmerging research
MeSHNeck Pain
1
Publications
13
Clinical trials
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 clinical trials expected to report results, the earliest in Q2 2027.
Upcoming Milestones
Major developments
Upcoming trial readoutHigh impact
Integrating Tailored Postoperative Opioid Tapering and Pain Management Support for Patients on Long-Term Opioid Use Presenting for Surgery
Results expected Q1 20282026-05-06
Upcoming trial readoutImportant
Safety and Efficacy of Oral Cannabis in Chronic Spine Pain
Results expected Q2 20272026-01-23
Clinical Milestones5View
Results expected 2
Recently completed 3
Activity timeline5

Clinical trials

12 sponsors · 2 new · 1 completed in the last 12 months (net +2)

The current development programme across all trial phases.

Clinical programme
13
All trials
5
Active
7
Late-stage
6
Completed
Late-stage studies

Phrenic Afferences In Organic and Metabolic Illness: Central Sensitization

Phase 4 · Recruiting · University of Seville

Integrating Tailored Postoperative Opioid Tapering and Pain Management Support for Patients on Long-Term Opioid Use Presenting for Surgery

Phase 3 · Recruiting · Stanford University

Safety and Efficacy of Oral Cannabis in Chronic Spine Pain

Phase 3 · Recruiting · University of Colorado, Denver

A Randomized, Placebo- and Active-controlled Multi-country, Multi-centre Parallel Group Study to Evaluate the Efficacy and Safety of a Fixed Dose Combination of 400 mg Ibuprofen and 100 mg Caffeine Compared to Ibuprofen 400 mg and Placebo in Patients With Acute Lower Back or Neck Pain.

Phase 3 · Completed · Boehringer Ingelheim

A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multicenter Trial to Study the Efficacy and Safety of Cyclobenzaprine HCl Extended Release (CER) 15 mg in Subjects With Acute Cervical and/or Lower Back Pain Due to Muscle Spasms of Local Origin

Phase 3 · Completed · Takeda

Prospective Randomized & Controlled Study of the Role of Low Doses Amitriptyline in the Management of Chronic Neck Pain

Phase 4 · Completed · St Joseph University, Beirut, Lebanon
Recruiting

Phrenic Afferences In Organic and Metabolic Illness: Central Sensitization

Phase 4 · Recruiting · University of Seville

Evaluation of the Efficacy of Adding Greater Occipital Nerve Block to Trigger Point Injection in Patients With Neck Pain and Upper Trapezius Trigger Points: A Single-Blind Randomized Controlled Trial

N/A · Recruiting · Ankara Etlik City Hospital

What is the Ability of Datamining Approaches to Cluster Patients With Idiopathic Neck Pain and Can Machine Learning Algorithms Provide More Efficient Rehabilitation and Less Recurrence Based on Kinaesthetic Training Protocols

N/A · Recruiting · University of Ljubljana

Integrating Tailored Postoperative Opioid Tapering and Pain Management Support for Patients on Long-Term Opioid Use Presenting for Surgery

Phase 3 · Recruiting · Stanford University

Safety and Efficacy of Oral Cannabis in Chronic Spine Pain

Phase 3 · Recruiting · University of Colorado, Denver
Recently completed

Comparison Of The Efficacy Of Interfascial Hydrodissection With A Mixture Of Lidocaine And Physiological Saline Solution Wıth 10% Dextrose In Patients With Chronic Neck Pain Associated With Resistant Myofascial Trigger Points In The Upper Trapezius

N/A · Completed · Ankara University

A Randomized, Placebo- and Active-controlled Multi-country, Multi-centre Parallel Group Study to Evaluate the Efficacy and Safety of a Fixed Dose Combination of 400 mg Ibuprofen and 100 mg Caffeine Compared to Ibuprofen 400 mg and Placebo in Patients With Acute Lower Back or Neck Pain.

Phase 3 · Completed · Boehringer Ingelheim

A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multicenter Trial to Study the Efficacy and Safety of Cyclobenzaprine HCl Extended Release (CER) 15 mg in Subjects With Acute Cervical and/or Lower Back Pain Due to Muscle Spasms of Local Origin

Phase 3 · Completed · Takeda

Prospective Randomized & Controlled Study of the Role of Low Doses Amitriptyline in the Management of Chronic Neck Pain

Phase 4 · Completed · St Joseph University, Beirut, Lebanon

Clinical Research on the Efficacy and Safety of East-West Collaborative Treatment Using NSAIDs and BV on Chronic Cervical Pain; A Randomized, Controlled, Parallel, Pilot Study

Phase 2 · Completed · Kyunghee University Medical Center

A Randomized, Double-blind, Placebo-controlled, Multi-center Parallel Group Phase IV Study to Evaluate the Efficacy and Safety of Diclofenac 1.16% Gel in Subjects With Acute Neck Pain

Phase 4 · Completed · Novartis

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes2
  • Global Burden of Disease1
  • Neck Pain1
Leading journals1
  • The Lancet. Rheumatology1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Discomfort or more intense forms of pain that are localized to the cervical region. This term generally refers to pain in the posterior or lateral regions of the neck.

Identifiers
MeSHNeck Pain
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.