Neoplasms, Experimental
Recent clinical, regulatory, research and industry developments relating to this disease.
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.
Human chimeric antigen receptor macrophages for cancer immunotherapy.
PDL1 Regulation by p53 via miR-34.
Exercise and the immune system: regulation, integration, and adaptation.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes8
- Antigens, Surface1
- Diet, Ketogenic1
- Exocytosis1
- Gastrointestinal Microbiome1
- HSP70 Heat-Shock Proteins1
- Immunity, Cellular1
- Immunotherapy, Adoptive1
- Milk Proteins1
Leading journals6
- The Journal of clinical investigation3
- Cancer research1
- Hepatology (Baltimore, Md.)1
- JCI insight1
- Journal of the National Cancer Institute1
- Nature biotechnology1
Leading researchers8
- Zhao L2
- Zitvogel L2
- Alves Costa Silva C1
- Amigorena S1
- Anderson NR1
- Aoki S1
- Aprahamian F1
- Araujo L1
Affiliations (unnormalised)6
- Aix Marseille Université1
- AJ Drexel Autism Institute1
- Angiogenesis Laboratory1
- Bloomberg~Kimmel Institute for Cancer Immunotherapy1
- Cancer Research Center1
- Center for Cellular Immunotherapies1
Disease biology
Key proteins & gene products studied in this disease. Number shows shared papers.
Related conditions
Diseases frequently studied alongside this one. Number shows shared papers.
Disease profile
A grounded synthesis of the condition — overview, causes, mechanism, risk factors and current standard of care.
Experimentally induced new abnormal growth of tissues in animals, used as a model system for studying human neoplasms. The literature grounding frames it as a research model rather than a clinical disease entity in humans.
It is experimentally induced in animals, so the proximate cause is deliberate experimental induction rather than a spontaneous natural etiology. The supplied grounding does not support additional causal factors.
The model is used to study neoplastic biology, including genetics, immunology, pathology, and radiotherapy-related aspects. Co-studied mechanisms indicate attention to programmed cell death pathways, immune checkpoints, the tumor microenvironment, gene expression regulation, and interactions with the gastrointestinal microbiome.
As a research model, it is not treated in the clinical sense. The grounding supports its use in experimental studies of neoplasms and in evaluating modalities such as radiotherapy and immunologic mechanisms, rather than a standard therapeutic care pathway.
AI-generated summary grounded in MeSH and 1 peer-reviewed source. Informational only — not medical advice. Generated 2026-07-07.
Reference
Authoritative identity, definition & identifiers.
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.