Neoplasms, Germ Cell and Embryonal
Recent clinical, regulatory, research and industry developments relating to this disease.
Adolescent and Young Adult Germ Cell Tumors: Epidemiology, Genomics, Treatment, and Survivorship.
Children's Oncology Group's 2023 blueprint for research: Germ cell tumors.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial with recent milestones.
Clinical MilestonesViewHide
- 2026-09-01Phase 1 Trial of Engineered HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsPrimary completion
- 2026-09-01ClinicalPhase 1 Trial of Engineered HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsPrimary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes3
- Neoplasms, Germ Cell and Embryonal2
- Neoplasm Recurrence, Local1
- Testicular Neoplasms1
Leading journals2
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology1
- Pediatric blood & cancer1
Leading researchers8
- Frazier AL2
- Poynter JN2
- Bagrodia A1
- Bhuta R1
- Dicken BJ1
- Feldman DR1
- Fung C1
- Gell JJ1
Affiliations (unnormalised)6
- Cancer and Blood Disease Institute1
- Centre for Cancer Genomics and Computational Biology1
- Dana Farber-Boston Children's Cancer and Blood Disorders Center1
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center1
- Division of Epidemiology and Clinical Research1
- Hasbro Children's Hospital1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Reference
Authoritative identity, definition & identifiers.
Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.