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Disease

Neuralgia, Postherpetic

Late-stage therapeutic developmentEmerging research
MeSHNeuralgia, Postherpetic
1
Publications
14
Clinical trials
2025
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial with recent milestones.
Clinical Milestones1View
Recently completed 1
Activity timeline1

Clinical trials

11 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
14
All trials
1
Active
6
Late-stage
6
Completed
Late-stage studies

High-Voltage Long-Duration Pulsed Radiofrequency Combined With Liposomal Bupivacaine Subcutaneous Block for Herpes Zoster-Associated Neuralgia

Phase 4 · Recruiting · Shirong Tan

A Multicentre, Single-Arm, Open-Label Study Of The Repeated Administration Of QUTENZA For The Treatment Of Peripheral Neuropathic Pain

Phase 4 · Completed · Astellas Pharma Inc

A LONG-TERM STUDY TO EVALUATE SAFETY AND EFFICACY STUDY OF PREGABALIN IN THE TREATMENT OF POSTHERPETIC NEURALGIA.

Phase 3 · Completed · Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

A Phase 2, Double Blind, Placebo Controlled, Dose-Ranging Study in Subjects With Postherpetic Neuralgia (PHN) to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Four Doses of TAK-583, Compared With Placebo

Phase 2/3 · Completed · Takeda

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Gabapentin Extended Release (G-ER) Tablets in the Treatment of Patients With Postherpetic Neuralgia

Phase 3 · Completed · Depomed

Lamictal in the Treatment of Post-Herpetic Neuralgia-A Safety, Efficacy,Randomized, Double Blind, Placebo Controlled, Cross-Over Study

Phase 2/3 · Terminated · George Washington University
Recently completed

A Multicentre, Single-Arm, Open-Label Study Of The Repeated Administration Of QUTENZA For The Treatment Of Peripheral Neuropathic Pain

Phase 4 · Completed · Astellas Pharma Inc

A Study of the Safety and Efficacy of AGN-214868 in Patients With Postherpetic Neuralgia

Phase 2 · Completed · Allergan

Study PXN110527: The Investigation of the Efficacy and Pharmacokinetics of XP13512 in Subjects With Neuropathic Pain Associated With Post-herpetic Neuralgia (PHN) Who Have Had an Inadequate Response to Gabapentin Treatment.

Phase 2 · Completed · XenoPort, Inc.

A LONG-TERM STUDY TO EVALUATE SAFETY AND EFFICACY STUDY OF PREGABALIN IN THE TREATMENT OF POSTHERPETIC NEURALGIA.

Phase 3 · Completed · Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

A Phase 2, Double Blind, Placebo Controlled, Dose-Ranging Study in Subjects With Postherpetic Neuralgia (PHN) to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Four Doses of TAK-583, Compared With Placebo

Phase 2/3 · Completed · Takeda

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Gabapentin Extended Release (G-ER) Tablets in the Treatment of Patients With Postherpetic Neuralgia

Phase 3 · Completed · Depomed

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

The Role of Cytokines in Postherpetic Neuralgia.

Journal of integrative neuroscience · 2025 · 1 cites
Recent publications

The Role of Cytokines in Postherpetic Neuralgia.

Journal of integrative neuroscience · 2025 · 1 cites
Major themes3
  • Cytokines1
  • Neuralgia, Postherpetic1
  • Neuroinflammatory Diseases1
Leading journals1
  • Journal of integrative neuroscience1
Leading researchers2
  • Lin P1
  • Shen Y1
Affiliations (unnormalised)2
  • Hangzhou Third People's Hospital1
  • The Fourth School of Clinical Medicine1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Pain in nerves, frequently involving facial SKIN, resulting from the activation the latent varicella-zoster virus (HERPESVIRUS 3, HUMAN). The two forms of the condition preceding the pain are HERPES ZOSTER OTICUS; and HERPES ZOSTER OPHTHALMICUS. Following the healing of the rashes and blisters, the pain sometimes persists.

Identifiers
MeSHNeuralgia, Postherpetic
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.