Paget's Disease, Extramammary
Recent clinical, regulatory, research and industry developments relating to this disease.
Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial expected to report results, the earliest in Q4 2027.
Clinical MilestonesViewHide
- 2025-08-24ClinicalIvonescimab (PD-1/VEGF Bispecpecial Antibody) in the Treatment of Multiple Advanced Tumors: a Multi-cohort, Multi-center, Single-arm Phase II StudyResults expected Q4 2027
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes1
- Vulvar Neoplasms1
Leading journals1
- Journal of the National Comprehensive Cancer Network : JNCCN1
Leading researchers8
- Abu-Rustum NR1
- Arend R1
- Barber E1
- Bradley K1
- Brooks R1
- Campos SM1
- Chino J1
- Chon HS1
Affiliations (unnormalised)6
- Abramson Cancer Center at the University of Pennsylvania.1
- Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.1
- City of Hope National Medical Center.1
- Dana-Farber/Brigham and Women's Cancer Center.1
- Duke Cancer Institute.1
- Fox Chase Cancer Center.1
Reference
Authoritative identity, definition & identifiers.
A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.