Back to discover
Disease

Periodontal Attachment Loss

Late-stage therapeutic developmentEmerging research
1
Publications
6
Clinical trials
2024
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q4 2027.

Clinical trials

6 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes2
  • Bacterial Load1
  • Periodontal Index1
Leading journals1
  • Journal of periodontal research1
Leading researchers6
  • Alibrandi A1
  • Isola G1
  • Kocher T1
  • Pesce P1
  • Polizzi A1
  • Santonocito S1
Affiliations (unnormalised)4
  • School of Dentistry1
  • University Medicine Greifswald1
  • University of Genoa1
  • University of Messina1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.