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Disease

Peutz-Jeghers Syndrome

Late-stage therapeutic developmentEmerging research
MeSHPeutz-Jeghers Syndrome
1
Publications
5
Clinical trials
3
Associated genes
2015
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q4 2028.
Upcoming Milestones
Major developments
Upcoming trial readoutImportant
The Cancer of the Pancreas Screening-5 CAPS5)Study
Results expected Q4 20282025-10-09
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

4 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
5
All trials
2
Active
1
Late-stage
0
Completed
Late-stage studies

The Cancer of the Pancreas Screening-5 CAPS5)Study

Phase 3 · Recruiting · Johns Hopkins University
Recruiting

Celecoxib for Prevention of Progression in Peutz-Jeghers Syndrome: A Double-blind, Randomized, Placebo-controlled Trial

N/A · Recruiting · Air Force Military Medical University, China

The Cancer of the Pancreas Screening-5 CAPS5)Study

Phase 3 · Recruiting · Johns Hopkins University

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Major themes2
  • Capsule Endoscopy1
  • Double-Balloon Enteroscopy1
Leading journals1
  • Endoscopy1
Leading researchers8
  • Adler SN1
  • Albert J1
  • Baltes P1
  • Barbaro F1
  • Cellier C1
  • Charton JP1
  • Delvaux M1
  • Despott EJ1
Affiliations (unnormalised)6
  • Catholic University1
  • Centre Hospitalier Lyon Sud1
  • Centro Hospitalar do Alto Ave1
  • Chaim Sheba Medical Center1
  • Clinical Psychology Unit1
  • Gedyt Endoscopy Center1

Associated genes

3 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

STK110.85CBARP0.15ZNF4440.00

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.

Identifiers
MeSHPeutz-Jeghers Syndrome
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.