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Disease

Precancerous Conditions

Clinical development underwayEmerging research
MeSHPrecancerous Conditions
2
Publications
5
Clinical trials
2019
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial with recent milestones (1 completed or reporting results).
Clinical Milestones1View
Results posted 1
Activity timeline1

Clinical trials

5 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
5
All trials
0
Active
0
Late-stage
5
Completed
Recently completed

Self-administered Artesunate Pessaries for Treatment of Cervical Precancer in Kenya

Phase 1 · Completed · UNC Lineberger Comprehensive Cancer Center

A Phase 1/2 Study of CPI-0610, a Small Molecule Inhibitor of BET Proteins: Phase 1 (Dose Escalation of CPI-0610 in Patients With Hematological Malignancies) and Phase 2 (Dose Expansion of CPI-0610 With and Without Ruxolitinib in Patients With Myeloproliferative Neoplasms)

Phase 1/2 · Completed · Constellation Pharmaceuticals

A Phase I Study of Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3)

Phase 1 · Completed · Johns Hopkins University

Phase I/II Study of Chemoprevention With Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Erlotinib (OSI-774, Tarceva) and Cyclooxygenase-2 (COX-2) Inhibitor (Celecoxib) in Premalignant Lesions of Head and Neck of Former Smokers

Phase 1/2 · Completed · Emory University

Clinical Protocol For A Phase II Double-Blind, Placebo-Controlled, Randomized Study Of Celecoxib (Sc-58635) In Oral Premalignant Lesions, Investigator IND

Phase 2 · Completed · Pfizer

Research activity

2 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20022019
Major themes5
  • Gastritis, Atrophic1
  • Helicobacter Infections1
  • Patient Care Management1
  • Precancerous Conditions1
  • Stomach Neoplasms1
Leading journals2
  • CA: a cancer journal for clinicians1
  • Endoscopy1
Leading researchers8
  • Annibale B1
  • Areia M1
  • Barros R1
  • Carneiro F1
  • Day TA1
  • Dinis-Ribeiro M1
  • Dumonceau JM1
  • Esposito G1
Affiliations (unnormalised)6
  • Center for Research in Health Technologies and Information Systems (CINTESIS)1
  • Centro Hospitalar de São João and Faculty of Medicine1
  • College of Dental Medicine1
  • Erasmus MC University Medical Center1
  • Faculté de Médecine Sorbonne Université1
  • Faculty of Medicine of the University of Porto1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Pathological conditions that tend eventually to become malignant.

Identifiers
MeSHPrecancerous Conditions
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.