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Disease

Presbycusis

Clinical development underwayEmerging research
1
Publications
3
Clinical trials
12
Associated genes
1
Related proteins
2020
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Age-Related Hearing Loss Is Dominated by Damage to Inner Ear Sensory Cells, Not the Cellular Battery That Powers Them.

Research2020-07-20The Journal of neuroscience : the official journal of the Society for Neuroscience

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial with recent milestones (1 completed or reporting results).
Clinical Milestones1View

Clinical trials

3 sponsors · 0 new · 1 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Age-Related Hearing Loss Is Dominated by Damage to Inner Ear Sensory Cells, Not the Cellular Battery That Powers Them.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020 · 213 cites
Recent publications

Age-Related Hearing Loss Is Dominated by Damage to Inner Ear Sensory Cells, Not the Cellular Battery That Powers Them.

The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020 · 213 cites
Leading journals1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience1
Leading researchers4
  • de Gruttola V1
  • Liberman MC1
  • O'Malley JT1
  • Wu PZ1
Affiliations (unnormalised)4
  • Eaton-Peabody Laboratories1
  • First Affiliated Hospital1
  • Harvard Medical School1
  • Harvard T.H. Chan School of Public Health1

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Gradual bilateral hearing loss associated with aging that is due to progressive degeneration of cochlear structures and central auditory pathways. Hearing loss usually begins with the high frequencies then progresses to sounds of middle and low frequencies.

Identifiers
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.