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Disease

Pressure Ulcer

Late-stage therapeutic developmentEmerging research
MeSHPressure Ulcer
1
Publications
15
Clinical trials
2019
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q2 2027.
Upcoming Milestones
Clinical Milestones2View
Results expected 1
Recently completed 1
Activity timeline2

Clinical trials

14 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
15
All trials
2
Active
7
Late-stage
6
Completed
Late-stage studies

Impact of Using Zinc Oxide Versus Moist Exposed Wound Ointment (MEBO) in Treatment of Second Stage Pressure Ulcer: A Randomized Control Clinical Trial

Phase 4 · Recruiting · King Abdullah Medical City

A Six Month Randomized Open-Label Trial of Pressure Ulcer Healing With Microcyn® Skin and Wound Care With Preservatives Versus Sterile Saline in Adult Spinal Cord Injury Subjects

Phase 4 · Completed · University of Alabama at Birmingham

Efficacy of Prontosan Solution on Chronic Ulcers

Phase 3 · Completed · Associazione Infermieristica per lo studio delle Lesioni Cutanee

Clinical Outcomes for Chronic Ulcers Treated With Clostridial Collagenase (SANTYL®) Versus Standard Care Within the Continuum of Care of an Accountable Care Organization (ACO)

Phase 4 · Withdrawn · Smith & Nephew, Inc.

Study Phase III, Randomized, Double-blind, Multicenter, National, to Evaluate the Non-inferiority in Efficacy of Investigational Product Regarding the Comparator Product, in Debridement of Devitalized Tissue in Uninfected Pressure Ulcers.

Phase 3 · Withdrawn · Cristália Produtos Químicos Farmacêuticos Ltda.

CSP #535 - Anabolic Steroid Therapy on Pressure Ulcer Healing in Persons With Spinal Cord Injury

Phase 3 · Terminated · US Department of Veterans Affairs
Recently completed

Development and Effectiveness Verification of an AI Application for Pressure Injury Nursing Based on Clinical Judgment Model

N/A · Completed · Yonsei University

The Effect of Prolotherapy in the Care of Pressure Injuries: A Randomized Controlled Study

Early Phase 1 · Completed · Fenerbahce University

A Six Month Randomized Open-Label Trial of Pressure Ulcer Healing With Microcyn® Skin and Wound Care With Preservatives Versus Sterile Saline in Adult Spinal Cord Injury Subjects

Phase 4 · Completed · University of Alabama at Birmingham

Insulin Complexation With Hydroxypropyl-beta-cyclodextrin: Spectroscopic Evaluation of Molecular Inclusion and Use of the Complex in Gel for Healing of Pressure Ulcers

Phase 1/2 · Completed · State University of Maringá

Efficacy of Prontosan Solution on Chronic Ulcers

Phase 3 · Completed · Associazione Infermieristica per lo studio delle Lesioni Cutanee

The Formation and Severity of Pressure Ulcers Associated With 4% Albumin vs. 0.9% Sodium Chloride Administration (Substudy of SAFE Protocol 153711)

Phase 1/2 · Completed · Bayside Health

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Leading journals1
  • Stem cell research & therapy1
Leading researchers8
  • Chen B1
  • Deng Z1
  • Li Q1
  • Niu X1
  • Sun Y1
  • Wang Y1
  • Yang Y1
  • Zhang J1
Affiliations (unnormalised)2
  • Institute of Microsurgery on Extremities1
  • Shanghai Jiao Tong University Affiliated Sixth People's Hospital1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.

Identifiers
MeSHPressure Ulcer
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.