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Disease

Prosthesis Failure

Active therapeutic pipelineEmerging research
MeSHProsthesis Failure
1
Publications
6
Clinical trials
2012
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Two-year outcomes after transcatheter or surgical aortic-valve replacement.

Research2012-03-26The New England journal of medicine

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q3 2027.
Upcoming Milestones
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

6 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
6
All trials
2
Active
0
Late-stage
4
Completed
Recruiting

Valve Hemodynamic Optimization Based on Doppler-Echocardiography Versus Catheterization Measurements Following Valve-in-Valve TAVR: A Prospective Randomized Trial

N/A · Recruiting · Institut universitaire de cardiologie et de pneumologie de Québec, University Laval

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Two-year outcomes after transcatheter or surgical aortic-valve replacement.

The New England journal of medicine · 2012 · 1,586 cites
Recent publications

Two-year outcomes after transcatheter or surgical aortic-valve replacement.

The New England journal of medicine · 2012 · 1,586 cites
Major themes1
  • Cardiac Catheterization1
Leading journals1
  • The New England journal of medicine1
Leading researchers8
  • Akin JJ1
  • Anderson WN1
  • Dewey TM1
  • Douglas PS1
  • Fischbein M1
  • Fontana GP1
  • Greason KL1
  • Hahn RT1
Affiliations (unnormalised)1
  • Columbia University Medical Center and New York Presbyterian Hospital1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.

Identifiers
MeSHProsthesis Failure
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.