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Disease

Pulmonary hypertension, primary, 4

Late-stage therapeutic development

Also known as KCNK3 primary pulmonary hypertension, primary pulmonary hypertension caused by mutation in KCNK3, pulmonary hypertension, primary, type 4, PPH4.

1
Clinical trials
1
Associated genes
1
Related proteins

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
1
All trials
0
Active
1
Late-stage
1
Completed
Late-stage studies
Phase 4 · Completed · Ottawa Heart Institute Research Corporation
Recently completed
Phase 4 · Completed · Ottawa Heart Institute Research Corporation

Evidence coverage

8 treatments

How much of this condition's readable clinical evidence the confidence engine has incorporated, across its most-studied treatments. This measures coverage of the evidence base — not whether any treatment works.

Substantial evidence coverage
66% · 73/111 eligible items incorporated
lowers systolic blood pressure in hypertension65%
lowers diastolic blood pressure in hypertension65%

Largest gap: no meaningful change (9, trial-readability).

Associated genes

1 match

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

1 match

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Synonyms

KCNK3 primary pulmonary hypertension, primary pulmonary hypertension caused by mutation in KCNK3, pulmonary hypertension, primary, type 4, PPH4

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.