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Disease

Retinal Neovascularization

Late-stage therapeutic developmentEmerging research
MeSHRetinal Neovascularization
1
Publications
8
Clinical trials
2008
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial with recent milestones.
Major developments
Major clinical milestoneWorth watching
Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin in Diabetic Macular Edema
Primary completion2025-09-22
Clinical Milestones1View
Recently completed 1
Activity timeline1

Clinical trials

6 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
8
All trials
1
Active
1
Late-stage
5
Completed
Late-stage studies

Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin in Diabetic Macular Edema

Phase 2/3 · Recruiting · Isfahan University of Medical Sciences
Recently completed

A Phase I/II Controlled Dose-escalating Trial to Establish the Baseline Safety and Efficacy of a Single Subretinal Injection of rAAV.sFlt-1 Into Eyes of Patients With Exudative Age-related Macular Degeneration (AMD)

Phase 1/2 · Completed · Lions Eye Institute, Perth, Western Australia

Topical Squalamine in the Treatment of Retinal Neovascularization From Proliferative Diabetic Retinopathy

Phase 2 · Completed · Elman Retina Group

A Phase 1, Open-Label, Multi-Center, Dose-Escalating, Safety and Tolerability Study of a Single Intravitreal Injection of AAV2-sFLT01 in Patients With Neovascular Age-Related Macular Degeneration

Phase 1 · Completed · Genzyme, a Sanofi Company

Panretinal Photocoagulation Versus Panretinal Photocoagulation Plus Intravitreous Ranibizumab for High Risk Proliferative Diabetic Retinopathy

Phase 2 · Completed · University of Sao Paulo

Intravitreal Injections With Avastin in Proliferative Retinopathies Related to the Production of VEGF Having Different Causes

Phase 2 · Completed · Ophthalmological Association Edelweiss

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Leading journals1
  • PloS one1
Leading researchers8
  • D'Amore PA1
  • Darland DC1
  • Kurihara T1
  • Maharaj AS1
  • Saint-Geniez M1
  • Sekiyama E1
  • Tucker BA1
  • Walshe TE1
Affiliations (unnormalised)1
  • Schepens Eye Research Institute1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina.

Identifiers
MeSHRetinal Neovascularization
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.