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Disease
Rupture, Spontaneous
Late-stage therapeutic developmentEmerging research
1
Publications
1
Clinical trials
2020
Latest publication
Latest activity
betaRecent clinical, regulatory, research and industry developments relating to this disease.
Research2020-04-23Circulation research
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
Executive briefingUpdating summary…Momentum: Low
Key developments
- 1 clinical trial with recent milestones (1 completed or reporting results).
Major developments
Major trial resultsHigh impact
Results posted2026-04-07
Clinical MilestonesViewHide
Activity timeline1
Clinical trials
The current development programme across all trial phases.
Clinical programme
1
0
1
1
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Most influential
Leading journals1
- Circulation research1
Leading researchers3
- Döring Y1
- Libby P1
- Soehnlein O1
Affiliations (unnormalised)5
- Brigham and Women's Hospital1
- German Center for Cardiovascular Research (DZHK)1
- Institute of Cardiovascular Prevention1
- Karolinska Institute1
- Swiss Cardiovascular Center1
Reference
Authoritative identity, definition & identifiers.
Defined in MeSH
Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.
Identifiers
References & data sources
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.