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Disease

Seborrheic keratosis

Late-stage therapeutic development

Also known as basal cell papilloma, keratosis Seborrheica, keratosis, seborrheic, somatic, keratosis, seborrheic.

6
Clinical trials
12
Associated genes
2
Related proteins
Current focus
Phosphatidylinositol 4 biologyTherapeutic developmentTumor p73 biology

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

2 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
6
All trials
0
Active
2
Late-stage
6
Completed
Recently completed

An Open-Label Study Assessing Subject Satisfaction With A-101 Hydrogen Peroxide Topical Solution, 40% (w/w) Treatment for Seborrheic Keratoses of the Face, Neck, and Decolletage

Phase 4 · Completed · Aclaris Therapeutics, Inc.

A Phase 2 Randomized, Double-Blind, Vehicle-Controlled, Parallel Group Study of the Safety and Effectiveness of A-101(Hydrogen Peroxide) Topical Solution in Subjects With Seborrheic Keratosis Lesions on the Trunk, Extremities, and Face

Phase 2 · Completed · Aclaris Therapeutics, Inc.

A Randomized, Double-Blind, Vehicle-Controlled, Parallel Group Study of the Safety and Effectiveness of A-101 Solution 40% in Subjects With Seborrheic Keratosis on the Trunk, Extremities and Face.

Phase 3 · Completed · Aclaris Therapeutics, Inc.

A Randomized, Double-Blind, Vehicle Controlled, Parallel Group Study of the Dose-Response Profile of A-101 Topical Solution in Subjects With Seborrheic Keratosis.

Phase 2 · Completed · Aclaris Therapeutics, Inc.

A Randomized, Double-Blind, Vehicle-Controlled, Within-Subject, Comparison Study of the Safety, Tolerability, And Effectiveness of A-101 Topical Solution in Subjects With Seborrheic Keratosis

Phase 1/2 · Completed · Aclaris Therapeutics, Inc.

A Phase 2a, Multi-Centre, Open-Label Study to Evaluate the Safety and Efficacy of PEP005(Ingenol Mebutate) Gel, 0.05%, in Patients With Seborrhoeic Keratosis on Non-head Locations

Phase 2 · Completed · Peplin

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

PIK3CA0.73CPVL0.45SEMA4B0.44ANKRD500.42PKP10.40TUFT10.38BHLHE400.37POU2F30.37PPL0.37ZFPM10.36KRT800.33HMCN10.31

Disease biology

2 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformvia PIK3CA0.73Tumor protein p73via TP730.28

Reference

Authoritative identity, definition & identifiers.

Synonyms

basal cell papilloma, keratosis Seborrheica, keratosis, seborrheic, somatic, keratosis, seborrheic

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.