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Disease

Sexually Transmitted Diseases

Late-stage therapeutic developmentEmerging researchSteady momentum
5
Publications
13
Clinical trials
1
Related conditions
2024
Latest publication

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Clinical trials

11 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
13
All trials
5
Active
7
Late-stage
6
Completed
Late-stage studies
Recently completed

Research activity

5 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20182024
Most influential
Recent publications
Major themes8
  • Sexually Transmitted Diseases2
  • Bacteria1
  • Betacoronavirus1
  • Bisexuality1
  • HIV Infections1
  • Homosexuality, Male1
  • Mpox, Monkeypox1
  • Proctitis1
Leading journals5
  • APMIS : acta pathologica, microbiologica, et immunologica Scandinavica1
  • JAMA network open1
  • Journal of acquired immune deficiency syndromes (1999)1
  • Lancet (London, England)1
  • Science (New York, N.Y.)1
Leading researchers8
  • Acosta-Velásquez KS1
  • Agud-Dios M1
  • Alemany A1
  • Anglade V1
  • Antón A1
  • Arando M1
  • Arroyo-Andrés J1
  • Baggaley RC1
Affiliations (unnormalised)6
  • Australian Research Centre in Sex1
  • Bio21 Molecular Science and Biotechnology Institute1
  • Center of Clinical Laboratory Medicine1
  • Central Clinical School1
  • Centre for Social Research in Health1
  • Centre for Tropical Medicine and Global Health1

Related conditions

1 match

Diseases frequently studied alongside this one. Number shows shared papers.

Disease profile

A grounded synthesis of the condition — overview, causes, mechanism, risk factors and current standard of care.

Overview

Sexually transmitted diseases are diseases that are caused by, or spread through, sexual contact. The term covers infections and related conditions transmitted during sexual behavior.

Causes

The grounding supports sexual contact as the route by which these diseases are propagated. It also links the topic to sexual behavior, including male homosexuality, as a co-studied mechanism, but does not support a more specific aetiology for the category as a whole.

Pathophysiology

The supplied material does not define a single biological mechanism for sexually transmitted diseases as a group. It does indicate that some sexually transmitted infections involve bacterial pathogens with antimicrobial resistance, and that bacterial vaginosis may alter cytokine levels and immune responses in the female reproductive tract.

Risk factors

Sexual behavior is the main supported risk factor in the grounding, because these diseases are propagated by sexual contact. The literature also highlights elevated STI risk in people using HIV preexposure prophylaxis and links bacterial vaginosis with acquisition of other STIs, but it does not support broader risk-factor statements for the category as a whole.

Current standard of care

The grounding supports diagnosis as a covered aspect, but it does not provide a general treatment standard for sexually transmitted diseases as a category. It does indicate that antimicrobial-resistant bacterial pathogens are managed with antimicrobial treatment informed by surveillance and whole-genome sequencing, and that some STI-related contexts involve HIV preexposure prophylaxis programs, but not a unified standard-of-care modality for all sexually transmitted diseases.

AI-generated summary grounded in MeSH and 3 peer-reviewed sources. Informational only — not medical advice. Generated 2026-07-07.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Diseases due to or propagated by sexual contact.

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.